inflammatory bowel disease

n. Abbr. IBD Any of several chronic disorders of the gastrointestinal tract, especially Crohn's disease and ulcerative colitis, characterized by inflammation and ulceration of the intestine and resulting in abdominal cramping and diarrhea.

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Noun

inflammatory bowel disease - inflammation of the coloncolitisCrohn's disease, regional enteritis, regional ileitis - a serious chronic and progressive inflammation of the ileum producing frequent bouts of diarrhea with abdominal pain and nausea and fever and weight lossirritable bowel syndrome, mucous colitis, spastic colon - recurrent abdominal pain and diarrhea (often alternating with periods of constipation); often associated with emotional stressulcerative colitis - a serious chronic inflammatory disease of the large intestine and rectum characterized by recurrent episodes of abdominal pain and fever and chills and profuse diarrheainflammation, redness, rubor - a response of body tissues to injury or irritation; characterized by pain and swelling and redness and heat

inflammatory bowel disease

any of various inflammatory diseases of the bowel whose etiology is unknown, including crohn's disease and ulcerative colitis.

inflammatory bowel disease (IBD),

general term for Crohn disease and ulcerative colitis, chronic disorders of the small and large intestine, of unknown cause, with conspicuous inflammatory features and distinctive but overlapping signs and symptoms.

inflammatory bowel disease

A general term for the symptoms associated with specific types of inflammation of the large intestine, including Crohn's disease–CD, ulcerative colitis–UC as well as idiopathic inflammatory bowel disease, a diagnosis of exclusion that clinically and pathologically mimics and/or overlaps CD and UC Heredity First-degree relatives of Pts with CD and UC have an 8- to 10-fold ↑ risk of developing the same form of colitis DiffDx Ischemia, radiation, uremia, cytotoxic drugs, heavy metal intoxication; IBD Pts often have ≥ 2 of following: Visible abdominal distension, relief of pain upon defecation, looser and more frequent bowel movements when the pain occurs; ♂:♀ ratio, 2:1; more common in Jews; IBD is associated with mucocutaneous disease–pyoderma gangrenosa, erythema nodosum, oral ulcers, annular erythema, vascular thromboses, epidermolysis bullosa, ocular disease–uveitis, iridocyclitis, hepatopathy–CAH, cirrhosis, sclerosing cholangitis, arthropathy–ankylosing spondylitis. Cf Irritable bowel syndrome Treatment Corticosteroids—or corticotropin–favored by some clinicians, aminosalicylates–sulfasalazine and 5-aminosalicylic acid, immunomodulatory agents–azathioprine, mercaptopurine, cyclosporine, MTX, metronidazole, antibiotics and nutritional support–both more effective in Crohn's disease, resulting in ↓ Sx, ↓ inflammatory sequelae, improved nutritional status. Inflammatory bowel disease
Clinical Ulcerative colitis Crohn's disease Rectal bleeding Common Rare Abdominal mass Rare 10-15% Abdominal pain Left-sided Right-sided Abnormal endoscopy 95% < 50% Perforation 12% 4% Colon carcinoma 5-10% Rare Response to steroids 75% 25% Surgical outcome Excellent Fair Rectal involvement > 95% !0% Radiology Ileal involvement Rare Usual Cross-hatched ulcers Rare Occasional Thumbprinting Absent Common Fissuring Absent Common Skip areas Absent Common Strictures Absent Common Pathology Distribution Diffuse Focal Superficial Transmural Mucosal atrophy Regeneration Marked Minimal Hyperemia Often marked Minimal Crypt abscess Common Rare Cytoplasmic mucin Decreased Intact Lymphoid aggregates Rare Common Lymph nodes Reactive hyperplasia ----- Edema Minimal Marked Granulomas Absent 60%

in·flam·ma·to·ry bow·el dis·ease

(IBD) (in-flam'ă-tōr-ē bow'ĕl di-zēz') General term for Crohn disease and ulcerative colitis, chronic disorders of the small and large intestine, autoimmune, with conspicuous inflammatory features and distinctive but overlapping signs and symptoms.

Inflammatory bowel disease (IBD)

Ulcerative colitis or Crohn's colitis; chronic conditions characterized by periods of diarrhea, bloating, abdominal cramps, and pain, sometimes accompanied by weight loss and malnutrition because of the inability to absorb nutrients.Mentioned in: Amebiasis, Menstrual Disorders, Sigmoidoscopy

inflammatory bowel disease

inflammatory bowel disease

inflammatory bowel disease

inflammatory bowel disease

inflammatory bowel disease

inflammatory bowel disease

inflammatory bowel disease (IBD),

inflammatory bowel disease

inflammatory bowel disease

in·flam·ma·to·ry bow·el dis·ease

Inflammatory bowel disease (IBD)

inflammatory bowel disease

Synonyms for inflammatory bowel disease

noun inflammation of the colon

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