单词 | interleukin-6 |
释义 | interleukin-6interleukin-6[‚in·tər¦lük·ən ′siks]interleukin-6in·ter·leu·kin-6(in'tĕr-lū'kin),IL6A gene on chromosome 7p21 that encodes interleukin-6, a cytokine which plays a role in the acute-phase response of inflammation and in B-cell maturation. It is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through Il-6 receptor alpha.Molecular pathology IL6 dysfunction is linked to increased susceptibility to diabetes and juvenile rheumatoid arthritis. in·ter·leu·kin-6(in'tĕr-lū'kin)Synonym(s): B-cell stimulatory factor 2. interleukin-6A CYTOKINE produced by HELPER T CELLS, MACROPHAGES, fibroblasts and MAST CELLS that promotes the growth and differentiation of B cells, T cells and blood stem cells and the induction of ACUTE PHASE PROTEINS. |
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