Infant Hercules Syndrome

A number of conditions have called infant Hercules syndrome
(1) Kocher-Debré-Semélaigne syndrome A clinical form of infant-onset hypothyroidism characterised by generalized enlargement of muscles that are weak with slowed reaction time, myxoedema, and cretinism
(2) Adrenogenital syndrome due to functional hyperplasia, adenomas or carcinomas of the adrenal cortex
(3) A case caused by mutation in the myostatin gene which resulted in both muscular hypertrophy and increased strength