| Acronym | Definition |
|---|
| HPCS➣High Performance Computing and Simulation (symposium) |
| HPCS➣High Performance Computing Systems |
| HPCS➣High Productivity Computing Systems |
| HPCS➣High Performance Computing Symposium |
| HPCS➣High Performance Communication Server |
| HPCS➣Harry Potter and the Chamber of Secrets (book/movie) |
| HPCS➣Hippotherapy Professional Clinical Specialist (American Hippotherapy Association; Damascus, PA) |
| HPCS➣Hewlett-Packard Cloud Services (computing) |
| HPCS➣High Pressure Core Spray system (commercial nuclear power - Boiling Water Reactor, BWR Type) |
| HPCS➣Hydridopolycarbosilane |