bacteremia

enUK

bacteremia:

see septicemiasepticemia
, invasion of the bloodstream by virulent bacteria that multiply and discharge their toxic products. The disorder, which is serious and sometimes fatal, is commonly known as blood poisoning.
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Bacteremia

the presence of bacteria in the blood. Bacteria enter the blood of man and animals through injuries of the skin and mucous membranes, and also when there are pathological changes in the lymph nodes, vascular system, and so on. Bacteremia accompanies many infectious diseases, such as leptospirosis, typhus, relapsing fever, and tularemia; it is especially characteristic of intestinal infections—typhoid, paratyphoid, and other salmonelloses; brucellosis, and others—in which it causes generalization of the pathologic process. Bacteremia is most intensely expressed during the acute (generalized) period of a disease. Bacteremia develops under the action of medium and large doses of ionizing radiation as a result of disruption of natural immunity. There is a decrease in the production of antibodies, a decrease in the number of leukocytes and of their phagocytic activity, and also changes in the permeability of tissue barriers and a number of other factors. Bacteremia is a characteristic complication of radiation sickness. As the organism overwhelms the disease (activation of the phagocytic function of the leukocytes, accumulation of antibodies, and so on), bacteremia decreases to the point of complete disappearance.

bacteremia

[′bak·tə′rē·mē·ə] (medicine) Presence of bacteria in the blood.

bacteremia

enUK

Bacteremia

Definition

Bacteremia is an invasion of the bloodstream by bacteria.

Description

Bacteremia occurs when bacteria enter the bloodstream. This may occur through a wound or infection, or through a surgical procedure or injection. Bacteremia may cause no symptoms and resolve without treatment, or it may produce fever and other symptoms of infection. In some cases, bacteremia leads to septic shock, a potentially life-threatening condition.

Causes and symptoms

Causes

Several types of bacteria live on the surface of the skin or colonize the moist linings of the urinary tract, lower digestive tract, and other internal surfaces. These bacteria are normally harmless as long as they are kept in check by the body's natural barriers and the immune system. People in good health with strong immune systems rarely develop bacteremia. However, when bacteria are introduced directly into the circulatory system, especially in a person who is ill or undergoing aggressive medical treatment, the immune system may not be able to cope with the invasion, and symptoms of bacteremia may develop. For this reason, bacteremia is most common in people who are already affected by or being treated for some other medical problem. In addition, medical treatment may bring a person in contact with new types of bacteria that are more invasive than those already residing in that person's body, further increasing the likelihood of bacterial infection.Conditions which increase the chances of developing bacteremia include:

immune suppression, either due to HIV infection or drug therapy
antibiotic therapy which changes the balance of bacterial types in the body
prolonged or severe illness
alcoholism or other drug abuse
malnutrition
diseases or drug therapy that cause ulcers in the intestines, e.g. chemotherapy for cancer

Common immediate causes of bacteremia include:

drainage of an abscess, including an abscessed tooth
urinary tract infection, especially in the presence of a bladder catheter
decubitus ulcers (pressure sores)
intravenous procedures using unsterilized needles, including IV drug use
prolonged IV needle placement
use of ostomy tubes, including gastrostomy (surgically making a new opening into the stomach), jejunostomy (surgically making an opening from the abdominal wall into the jejunum), and colostomy (surgically creating an articifical opening into the colon).

The bacteria most likely to cause bacteremia include members of the Staphylococcus, Streptococcus, Pseudomonas, Haemophilus, and Esherichia coli (E. coli) genera.

Symptoms

Symptoms of bacteremia may include:

fever over 101 °F (38.3 °C)
chills
malaise
abdominal pain
nausea
vomiting
diarrhea
anxiety
shortness of breath
confusion

Not all of these symptoms are usually present. In the elderly, confusion may be the only prominent symptom. Bacteremia may lead to septic shock, whose symptoms include decreased consciousness, rapid heart and breathing rates and multiple organ failures.

Diagnosis

Bacteremia is diagnosed by culturing the blood for bacteria. Samples may need to be tested several times over several hours. Blood analysis may also reveal an elevated number of white blood cells. Blood pressure is monitored closely; a decline in blood pressure may indicate the onset of septic shock.

Treatment

Bacteremia may cause no symptoms, but may be discovered through a blood test for another condition. In this situation, it may not need to be treated, except in patients especially at risk for infection, such as those with heart valve defects or whose immune systems are suppressed.

Prognosis

Prompt antibiotic therapy usually succeeds in clearing bacteria from the bloodstream. Recurrence may indicate an undiscovered site of infection. Untreated bacteria in the blood may spread, causing infection of the heart (endocarditis or pericarditis) or infection of the covering of the central nervous system (meningitis).

Prevention

Bacteremia can be prevented by preventing the infections which often precede it. Good personal hygiene, especially during viral illness, may reduce the risk of developing bacterial infection. Treating bacterial infections quickly and thoroughly can minimize the risk of spreading infection. During medical procedures, the burden falls on medical professionals to minimize the number and duration of invasive procedures, to reduce patients' exposure to sources of bacteria when being treated, and to use scrupulous technique.

Key terms

Colostomy — Surgical creation of an artificial anus on the abdominal wall by cutting into the colon and bringing it up to the surface.Gastrostomy — Surgical creation of an artificial opening into the stomach through the abdominal wall to allow tube feeding.Jejunostomy — Surgical creation of an opening to the middle portion of the small intestine (jejunum), through the abdominal wall.Septic shock — A life-threatening drop in blood pressure caused by bacterial infection.

Resources

Other

The Merck Page. April 13, 1998. http://www.merck.com.

bacteremia

[bak″ter-e´me-ah] the presence of bacteria in the blood. (See accompanying table.)

bac·te·re·mi·a

(bak'tēr-ē'mē-ă), The presence of viable bacteria in the circulating blood; may be transient following trauma such as dental or other iatrogenic manipulation or may be persistent or recurrent as a result of infection. Synonym(s): bacteriemia [bacteria + G. haima, blood]

bacteremia

(băk′tə-rē′mē-ə)n. The presence of bacteria in the blood.

bac′te·re′mic (-mĭk) adj.bac′te·re′mi·cal·ly adv.

bacteremia

The presence of bacteria in blood

bac·te·re·mi·a

(bak'tĕr-ē'mē-ă) The presence of viable bacteria in the circulating blood; may be transient following trauma such as dental or other iatrogenic manipulation or may be persistent or recurrent as a result of infection.
Synonym(s): bacteriemia, bacteraemia. [bacteria + G. haima, blood]

bac·te·re·mi·a

(bak'tĕr-ē'mē-ă) Presence of viable bacteria in circulating blood; may be transient following trauma such as dental or other iatrogenic manipulation or may be persistent or recurrent as a result of infection.
Synonym(s): bacteraemia. [bacteria + G. haima, blood]

bacteremia

bac·te·re·mi·a

bac•te•re•mi•a

bacteremia

bacteremia:

Bacteremia

bacteremia

bacteremia

Bacteremia

Definition

Description

Causes and symptoms

Causes

Symptoms

Diagnosis

Treatment

Prognosis

Prevention

Key terms

Resources

Other

bacteremia

bac·te·re·mi·a

bacteremia

bacteremia

bac·te·re·mi·a

bac·te·re·mi·a

bacteremia

Synonyms for bacteremia

noun transient presence of bacteria (or other microorganisms) in the blood

Synonyms

Related Words