IL1A


IL1A

A gene on chromosome 2q14 that encodes a protein belonging to the IL1 family of cytokines that is multifunctional and involved in various immune responses, inflammatory processes and haematopoiesis. It is produced by monocytes and macrophages as a proprotein, proteolytically processed, released in response to cell injury and induces apoptosis.
Molecular pathology
IL1 polymorphisms are associated with rheumatoid arthritis and Alzheimer's disease.