alphavirus
enUK| Noun | 1. | alphavirus - an arbovirus of the family Togaviridae that can cause a variety of encephalitis in horses |
| 单词 | alphavirus | |||
| 释义 | alphavirusenUK
alphavirusenUKAl·pha·vi·rus(al'fă-vī'rŭs),alphavirus(ăl′fə-vī′rəs)alphavirusA member of the group-IV Togaviridae, characterised by 70-nm virions surrounding a 40-nm isometric nucleocapsid, which contains a single-stranded linear RNA.Pathogenic alphaviruses Eastern, Western and Venezuela equine encephalitis viruses; Sindbis virus; Semliki Forest virus (which may be used as a vector for heterologous gene expression); Ross River; O’Nyong-Nyong virus. Epidemiology Pathogenic alphaviruses of the Western hemisphere occur primarily in the summer. Clinical findings Headache, fever, chills, nausea, vomiting, mental confusion, somnolence. Lab Lymphocytosis and increased protein in CSF. Management Supportive, intensive nursing care. Sequelae Neurologic effects (e.g., mental retardation), convulsions, paralysis in 30–70% of survivors. alphavirusGroup A arbovirus Virology A genus of the family Togaviridae characterized by 50-60 nm virions containing a single-stranded linear RNA Pathogenic alphaviruses Eastern, western, and Venezuela equine encephalitis viruses, Sindbis virus and Semliki Forest viruses–which may be used as vectors for expressing heterologous genes, Ross River, o'nyong-nyong virus Epidemiology Pathogenic alphaviruses of the Western hemisphere occur primarily in the summer Clinical Headache, fever, chills, N&V, mental confusion, somnolence Laboratory Lymphocytosis and ↑ protein in CSF Management Supportive, intensive nursing care Sequelae Neurologic effects–eg, mental retardation, convulsions, paralysis in 30–70% of survivorsAl·pha·vi·rus(al'fă-vī'rŭs)alphavirusenUK
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