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单词 griper
释义

griper


gripe

G0272900 (grīp)v. griped, grip·ing, gripes v.intr.1. Informal To complain naggingly or petulantly; grumble.2. To have sharp pains in the bowels.v.tr.1. Informal To irritate; annoy: Her petty complaints really gripe me.2. To cause sharp pain in the bowels of.3. To grasp; seize.4. To oppress or afflict.n.1. Informal A complaint.2. gripes Sharp, spasmodic pains in the bowels.3. A firm hold; a grasp.4. A grip; a handle.
[Middle English gripen, to seize, from Old English grīpan.]
grip′er n.
Thesaurus

griper

nounInformal. A person who habitually complains or grumbles:complainer, crab, faultfinder, grouch, growler, grumbler, grump, murmurer, mutterer, whiner.Informal: crank, grouser.Slang: bellyacher, sorehead, sourpuss.
EncyclopediaSeegripe

GRIP1


GRIP1

A gene on chromosome 12q13.13 that encodes a protein which is thought to play a role as a localized scaffold for assembling a multiprotein signalling complex and mediating trafficking of its binding partners at specific subcellular sites in neurons.
GRIP1 interacts with EFNB1, EFNB3, EPHA7, EPHB2, FRAS1, GRIA2, GRIA3, GRIPAP1/GRASP1, KIF5A, KIF5B, KIF5C, PLCD4, PPFIA1, PPFIA4, PRLHR, PTPRF, SLC30A9 and liprins-alpha. GRIP1 can form homomultimers or heteromultimers with GRIP2, and a ternary complex with GRIA2 and CSPG4. It interacts with ATAD1 in an ATP-dependent manner—ATAD1-catalysed ATP hydrolysis disrupts binding to ATAD1 and to GRIA2 and leads to AMPAR complex disassembly.

griper


Related to griper: Gripe water, gripper
  • noun

Synonyms for griper

noun a person who habitually complains or grumbles

Synonyms

  • complainer
  • crab
  • faultfinder
  • grouch
  • growler
  • grumbler
  • grump
  • murmurer
  • mutterer
  • whiner
  • crank
  • grouser
  • bellyacher
  • sorehead
  • sourpuss
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更新时间:2025/2/5 23:45:24