induced fit model

in·duced fit mod·el

1. a model to suggest a mode of action of enzymes in which the substrate binds to the active site of the protein, causing a conformational change in the protein; 2. Synonym(s): Koshland-Némethy-Filmer model

Koshland,

Daniel E., U.S. biochemist, 1920–. Adair-Koshland-Némethy-Filmer model - Synonym(s): Koshland-Némethy-Filmer modelKoshland-Némethy-Filmer model - a model to explain the allosteric form of cooperativity. Synonym(s): Adair-Koshland-Némethy-Filmer model; induced fit model