homocytotropic antibody

ho·mo·cy·to·tro·pic an·ti·bod·y

antibody usually of the IgE class that has an affinity for tissues (notably mast cells) of the same or a closely related species and that, on combining with specific antigen, triggers the release of pharmacologic mediators of anaphylaxis from the cells to which it is attached; the tropism seems to depend on the Fc portion of the antibody molecule; in anaphylaxis in the guinea pig, the homocytotropic antibody involved is of the γG class. Synonym(s): reagin (4) , reaginic antibody

ho·mo·cy·to·tro·pic an·ti·bod·y

(hō'mō-sī-tō-trō'pik an'ti-bod-ē) Antibody of the IgE class that has an affinity for tissues (notably mast cells) of the same or a closely related species and that, on combining with specific antigen, triggers the release of pharmacologic mediators of anaphylaxis from the cells to which it is attached.
Synonym(s): reaginic antibody.

ho·mo·cy·to·tro·pic an·ti·bod·y

(hō'mō-sī-tō-trō'pik an'ti-bod-ē) Antibody of the IgE class with an affinity for tissues of the same or a closely related species and that, on combining with specific antigen, triggers the release of pharmacologic mediators of anaphylaxis.
Synonym(s): reaginic antibody.

单词	homocytotropic antibody
释义	EncyclopediaSeereaginic antibody homocytotropic antibody ho·mo·cy·to·tro·pic an·ti·bod·y antibody usually of the IgE class that has an affinity for tissues (notably mast cells) of the same or a closely related species and that, on combining with specific antigen, triggers the release of pharmacologic mediators of anaphylaxis from the cells to which it is attached; the tropism seems to depend on the Fc portion of the antibody molecule; in anaphylaxis in the guinea pig, the homocytotropic antibody involved is of the γG class. Synonym(s): reagin (4) , reaginic antibody ho·mo·cy·to·tro·pic an·ti·bod·y (hō'mō-sī-tō-trō'pik an'ti-bod-ē) Antibody of the IgE class that has an affinity for tissues (notably mast cells) of the same or a closely related species and that, on combining with specific antigen, triggers the release of pharmacologic mediators of anaphylaxis from the cells to which it is attached. Synonym(s): reaginic antibody. ho·mo·cy·to·tro·pic an·ti·bod·y (hō'mō-sī-tō-trō'pik an'ti-bod-ē) Antibody of the IgE class with an affinity for tissues of the same or a closely related species and that, on combining with specific antigen, triggers the release of pharmacologic mediators of anaphylaxis. Synonym(s): reaginic antibody.
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