释义 |
EncyclopediaSeereaginic antibodyhomocytotropic antibody
ho·mo·cy·to·tro·pic an·ti·bod·yantibody usually of the IgE class that has an affinity for tissues (notably mast cells) of the same or a closely related species and that, on combining with specific antigen, triggers the release of pharmacologic mediators of anaphylaxis from the cells to which it is attached; the tropism seems to depend on the Fc portion of the antibody molecule; in anaphylaxis in the guinea pig, the homocytotropic antibody involved is of the γG class. Synonym(s): reagin (4) , reaginic antibodyho·mo·cy·to·tro·pic an·ti·bod·y (hō'mō-sī-tō-trō'pik an'ti-bod-ē) Antibody of the IgE class that has an affinity for tissues (notably mast cells) of the same or a closely related species and that, on combining with specific antigen, triggers the release of pharmacologic mediators of anaphylaxis from the cells to which it is attached. Synonym(s): reaginic antibody. ho·mo·cy·to·tro·pic an·ti·bod·y (hō'mō-sī-tō-trō'pik an'ti-bod-ē) Antibody of the IgE class with an affinity for tissues of the same or a closely related species and that, on combining with specific antigen, triggers the release of pharmacologic mediators of anaphylaxis. Synonym(s): reaginic antibody. |