histocompatibility

his·to·com·pat·i·bil·i·ty

H0217700 (hĭs′tō-kəm-păt′ə-bĭl′ĭ-tē)n. pl. his·to·com·pat·i·bil·i·ties A state or condition in which the absence of immunologic interference permits the grafting of tissue or the transfusion of blood without rejection.

his′to·com·pat′i·ble adj.

histocompatibility

(ˌhɪstəʊkəmˌpætɪˈbɪlɪtɪ) n (Biochemistry) the degree of similarity between the histocompatibility antigens of two individuals. Histocompatibility determines whether an organ transplant will be tolerated ˌhistocomˈpatible adj

his•to•com•pat•i•bil•i•ty

(ˌhɪs toʊ kəmˌpæt əˈbɪl ɪ ti)

n. the condition of being similar antigenic types such that cells or tissues transplanted from a donor to a recipient are not rejected. [1945–50]

Thesaurus

Noun

histocompatibility - condition in which the cells of one tissue can survive in the presence of cells of another tissue; "a successful graft or transplant requires a high degree of histocompatibility"organic phenomenon - (biology) a natural phenomenon involving living plants and animals

Translations

histocompatibility

histocompatibility:

see transplantation, medicaltransplantation, medical,
surgical procedure by which a tissue or organ is removed and replaced by a corresponding part, usually from another part of the body or from another individual.
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Histocompatibility

A term used to describe the genes that influence acceptance or rejection of grafts. When grafts of tissue are exchanged between genetically dissimilar individuals, profound immunological rejection generally takes place. In contrast, grafts between genetically similar individuals, such as identical twins, are normally tolerated; they are histocompatible. Most known examples of histocompatibility (or H) genes encode polymorphic (that is, tending to differ between individuals) cell-surface proteins.

The major histocompatibility complex (MHC) contains a set of histocompatibility genes, termed major because mismatching at these genes invokes rapid rejection. The main function of MHC genes involves distinguishing self from nonself in the immune system, as part of preventing the spread of infectious disease. The body employs special mechanisms to avoid rejection of the fetus, which is effectively an allograft, that is, a graft from a donor to a genetically dissimilar recipient of the same species; in this case, the mechanisms include a diminution of MHC gene expression.

The MHC contains a spectrum of genes, many of which influence processing and presentation of antigens to the immune system. In mice, the MHC is designated the H-2 complex; in humans, it is referred to as the HLA complex (for human leukocyte A system). Mice and other mammals seem to have a similar arrangement of genes in their MHCs. See Antigen, Cellular immunology, Mendelism, Transplantation biology

histocompatibility

[¦hi·stō·kəm′pad·ə′bil·əd·ē] (immunology) The capacity to accept or reject a tissue graft.

histocompatibility

[his″to-kom-pat″ĭ-bil´ĭ-te] 1. the quality of a cellular or tissue graft enabling it to be accepted and functional when transplanted to another organism.2. the degree to which two individuals are histocompatible. adj., adj histocompat´ible.

his·to·com·pat·i·bil·i·ty

(his'tō-kom-pat'i-bil'i-tē), A state of immunologic similarity (or identity) that permits successful homograft transplantation.

histocompatibility

(hĭs′tō-kəm-păt′ə-bĭl′ĭ-tē)n. pl. histocompatibili·ties A state or condition in which the absence of immunologic interference permits the grafting of tissue or the transfusion of blood without rejection.

his′to·com·pat′i·ble adj.

his·to·com·pat·i·bil·i·ty

(his'tō-kŏm-pat'i-bil'i-tē) A state of immunologic similarity (or identity) that permits successful homograft transplantation.

histocompatibility

Sufficient affinity between the genetic composition (genotypes) of donor and host to allow successful tissue or organ grafting.

histocompatibility

the acceptance by a recipient of tissue transplanted from a donor, a state that is determined by histocompatability ANTIGENS.

Histocompatibility

The major histocompatibility determinants are the human leukocyte antigens (HLA) and characterize how well the patient and donor are matched.Mentioned in: Bone Marrow Transplantation

his·to·com·pat·i·bil·i·ty

(his'tō-kŏm-pat'i-bil'i-tē) State of immunologic similarity that permits successful homograft transplantation.

histocompatibility

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histocompatibility

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histocompatibility:

Histocompatibility

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Histocompatibility

his·to·com·pat·i·bil·i·ty

histocompatibility

Words related to histocompatibility

noun condition in which the cells of one tissue can survive in the presence of cells of another tissue

Related Words