aplastic anaemia
| Noun | 1. |  aplastic anaemia - anemia characterized by pancytopenia resulting from failure of the bone marrow; can be caused by neoplasm or by toxic exposure |
| 单词 | aplastic anaemia | |||
| 释义 | aplastic anaemia
aplastic anaemiaaplastic anaemiaAnaemia due to a failure in marrow production of RBCs, often accompanied by failure in WBC and platelet production (i.e., granulocytopaenia, thrombocytopaenia).Aetiology Toxins (benzene, toluene, insecticides), radiotherapy, drugs (carbamazepine, chemotherapy, chloramphenicol, gold salts, phenytoin, phenylbutazone, quinacrine, sulfonamides, tolbutamide), autoimmunity, SLE, post-hepatitis, pregnancy, paroxysmal nocturnal haemoglobinuria. Prognosis Aplastic anaemia is often unresponsive to specific therapy. aplastic anaemiaA serious form of anaemia in which no new blood cells are formed in the bone marrow. About 30% of cases follow virus infections, especially MEASLES, MUMPS and HEPATITIS or are induced by drugs such as BUTAZOLIDINE, SULPHONAMIDES, CHLORAMPHENICOL or dipyrone. The condition results from damage to the haemopoietic stem cells often from an autoimmune process that can be checked by immunosuppressive drug treatment. Blood transfusions are often necessary to maintain life.aplastic anaemia
Synonyms for aplastic anaemia
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