| Acronym | Definition |
|---|
| HOTD➣House of the Dead (Sega game) |
| HOTD➣Hair of the Dog |
| HOTD➣Horns of the Demon (gaming, Gaia Online) |
| HOTD➣High School of the Dead (manga, anime) |
| HOTD➣Hottie of the day |
| HOTD➣Helm of the Dominator (gaming) |
| HOTD➣Hands on Test Drive |
| HOTD➣Highlight of the Day |
| HOTD➣Home of the Underdogs (gaming website) |
| HOTD➣Head of Train Device |
| HOTD➣Heroine of the Dragon |
| HOTD➣HID (Hughes Identification Devices) on the Desktop (information technology security) |