herpes simplex encephalitis virus

her·pes sim·plex en·ceph·a·li·tis vi·rus

(hĕr'pēz sim'pleks en-sef'ă-lī'tis vī'rŭs) The most common acute encephalitis, caused by herpes simplex virus-1; affects people of any age; preferentially involves the inferomedial portions of the temporal lobe and the orbital portions of the frontal lobes; pathologically, severe hemorrhagic necrosis is present along with, in the acute stages, intranuclear eosinophilic inclusion bodies in the neurons and glial cells.