immunodeficiency disease, severe combined

SCID

Any of a group of inherited autosomal or X-linked recessive disorders in which there is partial or complete dysfunction of the immune system. Defects are present in both B- and T-cell–mediated immunity responses and frequently include defective cytokine function. Within 6 months after birth, babies develop infections from bacterial, viral, fungal, or protozoan organisms. Intravenous immune globulin (IVIG) is given to provide antibodies, but a successful bone marrow transplant is required to prevent death. The efficacy of gene therapy is under investigation. See: cytokine; cell-mediated immunity; humoral immunity

单词	immunodeficiency disease, severe combined
释义	DictionarySeeSCID immunodeficiency disease, severe combined immunodeficiency disease, severe combined , SCID Any of a group of inherited autosomal or X-linked recessive disorders in which there is partial or complete dysfunction of the immune system. Defects are present in both B- and T-cell–mediated immunity responses and frequently include defective cytokine function. Within 6 months after birth, babies develop infections from bacterial, viral, fungal, or protozoan organisms. Intravenous immune globulin (IVIG) is given to provide antibodies, but a successful bone marrow transplant is required to prevent death. The efficacy of gene therapy is under investigation. See: cytokine; cell-mediated immunity; humoral immunity
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