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EncyclopediaSeeWerdnig-Hoffmann diseaseHoffmann, Johann
Hoffmann, Johann (hof'man, 'man?) Ger. neurologist, 1857–1919. Hoffmann reflexAn abnormal reflex found in patients with damaged pyramidal tracts of the brain. Flexion of the distal interphalangeal joint of the middle finger makes the thumb of the same hand flex and adduct. Synonym: Hoffmann signHoffmann signHoffmann reflex.Hoffmann, Johann, German neurologist, 1857-1919. Hoffmann muscular atrophy - progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves. Synonym(s): infantile spinal muscular atrophyHoffmann phenomenon - excessive irritability of the sensory nerves to electrical or mechanical stimuli in tetany.Hoffmann reflex - Synonym(s): Hoffmann signHoffmann sign - in latent tetany, mild mechanical stimulation of the trigeminal nerve causes severe pain. Synonym(s): Hoffmann reflexWerdnig-Hoffmann disease - Synonym(s): Werdnig-Hoffmann muscular atrophyWerdnig-Hoffmann muscular atrophy - see under Werdnig |