| Acronym | Definition |
|---|
| HDE➣Humanitarian Device Exemption |
| HDE➣Hybrid Diesel-Electric |
| HDE➣Hauptverband des Deutschen Einzelhandels (Central Association of German Retail Trade) |
| HDE➣High Definition Encoder (various companies) |
| HDE➣Help Desk Essentials (certification) |
| HDE➣Hybrid Detection Engine |
| HDE➣High Definition Encoder |
| HDE➣Horizon Digital Enterprise, Inc. (Japan) |
| HDE➣Heavy-Duty Engine |
| HDE➣Higher Diploma in Education (UK) |
| HDE➣Heroldo de Esperanto (Esperanto: Esperanto Herald; magazine; est. 1920) |
| HDE➣Home Decor Exchange |
| HDE➣Holdrege, Nebraska (airport code) |
| HDE➣Héroes de la Educación (Spanish: Heroes of Education; Guatemala) |
| HDE➣Hottest Deals Ever (Allentown, PA) |
| HDE➣Hypertext Document Engineering |
| HDE➣Heater Drive Electronics |
| HDE➣Home Docking Environment |
| HDE➣Historical Data Entry |
| HDE➣Highly Distributed Environment |
| HDE➣Hacking Defined Experts (course) |
| HDE➣Number of Honeydew Elements |