单词 | gpm6a |
释义 | GPM6AGPM6AA gene on chromosome 4q34 that encodes a multipass membrane protein involved in neuronal differentiation, migration of neuronal stem cells, neuronal plasticity, filopodia motility and probably synapse formation. It may be involved in neuronal NGF-dependent Ca2+ influx, regulating endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs), and in enhancing internalisation and recycling of mu-type opioid receptors. |
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