ADAM1dda33

ADAM1dda33

A type I transmembrane protein of the ADAMs family which is encoded by ADAM33 on chromosome 20p13. ADAM33 mRNA is highly expressed in smooth muscle-containing organs, in duodenal granulation tissue, and in subepithelial fibroblasts and smooth muscle but not respiratory epithelium of asthmatics, which suggests that ADAM33 has a pathophysiologic role in asthma.