| 释义 |
hobnail cell hob·nail cellcell characteristic of a clear cell adenocarcinoma; a round expansion of clear cytoplasm projects into the lumen of neoplastic tubules, but the basal part of the cell containing the nucleus is narrow.A cell that juts above an adjacent epithelial or endothelial surface or lining; the hobnail pattern’s significance differs according to the organ, and it can be neoplastic—as in mesonephroid-type ovarian cystadenocarcinoma, clear cell carcinoma, endometrial carcinoma, collecting duct carcinoma, mesotheliomas—or reactive, as the jutting of type II pneumocytes above the alveolar lining in lungs with diffuse alveolar damage or the bulging of succulent, secretion-filled, vacuolated, enlarged and pleomorphic apocrine cells in the lobules of a lactating breasthob·nail cell (hob'nāl sel) A cell characteristic of a clear cell adenocarcinoma; a round expansion of clear cytoplasm projects into the lumen of neoplastic tubules, but the basal part of the cell containing the nucleus is narrow. |