unhinge
From Longman Dictionary of Contemporary Englishunhingeun‧hinge /ʌnˈhɪndʒ/ verb [transitive] CRAZYto make someone become very upset or mentally ill The terrible experience seemed to have unhinged him slightly. —unhinged adjective→ See Verb tableExamples from the Corpusunhinge• Although Kazrik survived, the experienced has unhinged him somewhat.• The stress of the job has unhinged many workers.