ruination
From Longman Dictionary of Contemporary Englishruinationru‧in‧a‧tion /ˌruːəˈneɪʃən/ noun [uncountable] old-fashioned SPOILa process in which someone or something is ruined, or the cause of this – often used humorouslyExamples from the Corpusruination• And general commercial malpractice causes the ruination of thousands more people.