: an enzyme or complex of enzymes that promotes the conversion of an androgen into estrogen
Example Sentences
Recent Examples on the WebMany supplements contain aromatase inhibitors, which assist to maintain free testosterone levels high.The Salt Lake Tribune, 25 May 2022 Other drugs called aromatase inhibitors completely stop the production of estrogen—giving estrogen-receptor positive cancer nothing to work with. Jessie Van Amburg, Health.com, 16 Sep. 2021 And all naturally occurring estrogen in humans was once testosterone, transformed into estrogen by the enzyme aromatase. Grace Huckins, Scientific American, 1 Feb. 2021 All participants were given standard hormone therapy (an aromatase inhibitor or tamoxifen) as well as a medication that shuts down the ovaries' production of estrogen. Samantha Lauriello, Health.com, 4 June 2019 All of the women were given standard hormonal therapy -- an aromatase inhibitor or tamoxifen -- plus a medication that shuts down the ovaries' production of estrogen. Amy Norton, CBS News, 3 June 2019 But the effect that’s best understood is fat tissue’s ability to convert circulating steroids into estrogen via the enzyme aromatase, Dr. Jensen explains. Sarah Jacoby, SELF, 26 June 2018 According to the World Anti-Doping Agency, letrozole is an aromatase inhibitor that can act as a hormonal and metabolic stimulant by increasing testosterone concentration. Bianca Britton, CNN, 12 June 2018 This happened, the group theorized, because AMH damped down levels of aromatase, an enzyme in the placenta that usually converts testosterone to a form of estrogen. Jennifer Couzin-frankel, Science | AAAS, 14 May 2018 See More
Word History
Etymology
aromat(ize) + -ase
First Known Use
1959, in the meaning defined above
Medical Definition
aromatase
noun
aro·ma·tase ə-ˈrō-mə-ˌtās, -ˌtāz
: an enzyme or complex of enzymes that promotes the conversion of an androgen (as testosterone) into estrogens (as estradiol)