单词	thalassemia
释义	thalassemia noun thal·​as·​se·​mia ˌtha-lə-ˈsē-mē-ə  : any of a group of inherited disorders of hemoglobin synthesis (such as Cooley's anemia) that are marked by mild to severe hypochromic and microcytic anemia, result from the partial or complete failure in production of one or more globin chains, and tend to occur especially in individuals of Mediterranean, African, or southeastern Asian ancestry —sometimes used with a prefix (such as alpha-, beta-, or delta-) to indicate the hemoglobin chain affected see beta-thalassemia thalassemic ˌtha-lə-ˈsē-mik  adjective or noun Example Sentences Recent Examples on the Web Many will address diseases suffered by vastly larger populations than those with beta thalassemia. Michael Hiltzik, Los Angeles Times, 9 Sep. 2022 Gene therapy is an entirely new way of treating beta thalassemia, which in its most severe form tethers patients to chronic blood transfusions and other medical procedures, and shortens their lifespan. Adam Feuerstein, STAT, 22 Aug. 2022 Agios is conducting additional studies to expand the use of the drug to include children with PK deficiency and other diseases affecting red blood cells, including thalassemia and sickle cell disease. Adam Feuerstein, STAT, 18 Feb. 2022 For rows with thalassemia or angiogram data present (and none of them had both), the accuracy went up to 71 percent—not great, but not terrible. Sean Gallagher, Ars Technica, 9 Aug. 2022 Beti-cel helped people with the rare blood disease beta-thalassemia stay off blood transfusions by supplying them with a gene needed to ferry oxygen throughout the body. Globe Staff, BostonGlobe.com, 19 June 2022 Following a one-time infusion, all 31 of the patients with sickle cell reported being free from episodes of severe pain; 42 of the 44 patients with beta-thalassemia no longer required blood transfusions. Adam Feuerstein, STAT, 13 June 2022 This is because most beta thalassemia patients - presumably less severely impacted - could remain on the existing standard of care. Joshua Cohen, Forbes, 5 May 2022 But Saturday, Bluebird relied largely on European patients enrolled in its beta-thalassemia clinical trials to demonstrate the successful, long-term durability of Zynteglo. Adam Feuerstein, STAT, 15 Dec. 2021 See More Word History Etymology New Latin, from Greek thalassa sea + New Latin -emia First Known Use 1932, in the meaning defined above Phrases Containing thalassemia beta-thalassemia thalassemia major thalassemia minor beta-thalassemia thalassemia major thalassemia minor Medical Definition thalassemia noun thal·​as·​se·​mia variants or British thalassaemia ˌthal-ə-ˈsē-mē-ə  : any of a group of inherited hypochromic anemias and especially Cooley's anemia controlled by a series of allelic genes that cause reduction in or failure of synthesis of one of the globin chains making up hemoglobin and that tend to occur especially in individuals of Mediterranean, African, or southeastern Asian ancestry —sometimes used with a prefix (as alpha-, beta-, or delta-) to indicate the hemoglobin chain affected called also Mediterranean anemia see alpha-thalassemia, beta-thalassemia
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