: a test for identifying potential carcinogens by studying their mutagenic effect on bacteria
Word History
Etymology
Bruce N. Ames born 1928 American biochemist
First Known Use
1974, in the meaning defined above
Medical Definition
Ames test
noun
ˈāmz-
variants also Ames assay
: a test for identifying potential carcinogens by studying the frequency with which they cause histidine-producing genetic mutants in bacterial colonies of the genus Salmonella (S. typhimurium) initially lacking the ability to synthesize histidine
The compound … produced the highest score ever reported in an Ames test, a standard measure of the cancer-causing potential of toxic chemicals.Today's Chemist at Work
Dimethylnitrosamine … a known animal carcinogen—is usually a potent mutagen in the Ames assay.Science News