Recent Examples on the WebAs with any hair removal method that involves pulling hair from the root, there are still some risks of side effects such as temporary skin redness, inflamed hair follicles, hyperpigmentation, depigmentation (loss of skin color), and ingrown hairs. Stephanie Eckelkamp, SELF, 22 Dec. 2021 Although vitiligo is typically a lifelong condition, Farber says that those who have it are not born with this depigmentation. Rebecca Dancer, Allure, 14 Aug. 2020 Long-term use of it can lead to irritation, skin sensitivity, permanent depigmentation and in rare cases, ochronosis, an additional darkening of the skin that is often blue or black in color. Rebecca Dancer, Allure, 12 Mar. 2020