prion

1 of 2

noun (1)

pri·on ˈprī-ˌän How to pronounce prion (audio)

: any of several small petrels (genus Pachyptila of the family Procellariidae) of the southern hemisphere that are bluish gray above and white below

prion

2 of 2

noun (2)

pri·on ˈprē-ˌän How to pronounce prion (audio)

: prion protein

A prion is a protein of unknown function that resides on the surface of brain cells.

Sidney Perkowitz

especially : an abnormal form of prion protein that in mammals includes pathogenic forms which arise sporadically, as a result of genetic mutation, or by transmission (as by ingestion of infected tissue) and which upon accumulation in the brain cause a prion disease (such as bovine spongiform encephalopathy or Creutzfeldt-Jakob disease)

Abnormal proteins, known as prions, may trigger mad-cow disease simply by coming into contact with healthy proteins in the brain.

Time

… the infectious prion conformation replicates itself in a host by catching the 'benign' host prion protein and forcing it into the infectious conformation.

Roland Riek

单词	prion
释义	prion 1 of 2 noun (1) pri·on ˈprī-ˌän : any of several small petrels (genus Pachyptila of the family Procellariidae) of the southern hemisphere that are bluish gray above and white below prion 2 of 2 noun (2) pri·on ˈprē-ˌän : prion protein A prion is a protein of unknown function that resides on the surface of brain cells. Sidney Perkowitz especially : an abnormal form of prion protein that in mammals includes pathogenic forms which arise sporadically, as a result of genetic mutation, or by transmission (as by ingestion of infected tissue) and which upon accumulation in the brain cause a prion disease (such as bovine spongiform encephalopathy or Creutzfeldt-Jakob disease) Abnormal proteins, known as prions, may trigger mad-cow disease simply by coming into contact with healthy proteins in the brain. Time … the infectious prion conformation replicates itself in a host by catching the 'benign' host prion protein and forcing it into the infectious conformation. Roland Riek Word History Etymology Noun (1) New Latin, from Greek priōn saw, from priein to saw; from its sawlike bill Noun (2) proteinaceous + infectious + -on entry 2 First Known Use Noun (1) 1848, in the meaning defined above Noun (2) 1982, in the meaning defined above Phrases Containing prion prion disease prion protein prion disease prion protein Medical Definition prion noun pri·on ˈprē-ˌän : any of various infectious proteins that are abnormal forms of normal cellular proteins, that proliferate by inducing the normal protein to convert to the abnormal form, and that in mammals include pathogenic forms which arise sporadically, as a result of genetic mutation, or by transmission (as by ingestion of infected tissue) and which upon accumulation in the brain cause a prion disease
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prion

noun (1)

noun (2)

Word History

Phrases Containing prion

Medical Definition

noun