单词	cyclooxygenase
释义	cyclooxygenase noun cy·​clo·​ox·​y·​gen·​ase ˌsī-klō-ˈäk-si-jə-ˌnās  : an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins and that has two isoforms of which one is involved in the creation of prostaglandins which mediate inflammation and pain Word History Etymology cycl- + oxygenase, an enzyme, from oxygen + -ase First Known Use 1974, in the meaning defined above Medical Definition cyclooxygenase noun cy·​clo·​ox·​y·​gen·​ase ˌsī-klō-ˈäk-si-jə-ˌnās  -äk-ˈsij-ə-  -ˌnāz : an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins, that is inactivated by aspirin and other NSAIDs, and that has two isoforms of which one is involved in the cascade of events producing the pain and inflammation of arthritis and the other is not see cox-1, cox-2
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