单词	major depressive disorder
释义	major depressive disorder noun : a serious mood disorder involving one or more episodes of intense psychological depression or loss of interest or pleasure that lasts two or more weeks and is accompanied by irritability, fatigue, poor concentration, sleep disturbances, weight gain or loss, feelings of worthlessness or guilt, and sometimes suicidal tendencies : clinical depression, major depression About 18 million Americans are diagnosed with a major depressive disorder each year. David Schwab The most serious form of depression is major depressive disorder, characterized by depressed mood, loss of interest or pleasure, changes in appetite, increased or decreased sleep, increased or decreased motor activity, fatigue, feelings of worthlessness or guilt, difficulty concentrating and, for some people, recurrent thoughts of death or suicide. Sandi Lloyd —abbreviation MDD Example Sentences Recent Examples on the Web One study from the Chongqing Medical University in China found that the gut microbiomes of people diagnosed with major depressive disorder were very different from those of the general population. Laura Newberry, Los Angeles Times, 13 Sep. 2022 The drug, a once-daily oral treatment known as PRAX-114, missed its primary and secondary goals in a study enrolling about 200 patients with major depressive disorder. Damian Garde, STAT, 8 June 2022 And a study by the American Heart Association found that a diagnosis of major depressive disorder was associated with an average of 27 lost work days annually per employee, costing employers $4,426 a year. Georgina Miranda, Outside Online, 25 Aug. 2021 The drugs included Abilify for mood disorders; Zoloft, Trazodone and Clonidine for sleep issues; Ritalin, Adderall, Qelbree and Vyvanse for A.D.H.D.; and Remeron for major depressive disorder. New York Times, 10 May 2022 People who suffer from major depressive disorder are at higher risk of suicide, according to NAMI. Lisa Bain, Good Housekeeping, 20 May 2022 This includes general major depressive disorder, postpartum depression, seasonal affective disorder and bipolar disorder. Nicole Pajer, PEOPLE.com, 10 June 2022 Doctors may prescribe Wellbutrin to treat either major depressive disorder or seasonal affective disorder, which is when depression episodes tend to come in the Fall and Winter months. Bruce Y. Lee, Forbes, 30 Apr. 2022 For some disorders, such as ADHD, major depressive disorder (MDD), and psychotic disorders, medication reduced the incidence of substance abuse down the road. Stephanie H. Murray, The Week, 31 May 2022 See More Word History First Known Use 1977, in the meaning defined above Medical Definition major depressive disorder noun : a serious mood disorder involving one or more episodes of intense psychological depression or loss of interest or pleasure that lasts two or more weeks and is accompanied by irritability, fatigue, poor concentration, sleep disturbances, weight gain or loss, feelings of worthlessness or guilt, and sometimes suicidal tendencies : clinical depression, major depression The diagnosis of both major depressive disorder and subsyndromal symptoms is complicated by difficulties that elderly patients may have in recognizing or describing depressive symptoms. Lawrence M. Martin et al., The John Hopkins White Papers —abbreviation MDD
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