hyaluronidase
noun
hy·al·uron·i·dase ˌhī(-ə)l-yu̇-ˈrä-nə-ˌdās 
-ˌdāz
: a mucolytic enzyme that facilitates the spread of fluids through tissues by lowering the viscosity of hyaluronic acid
Example Sentences
Recent Examples on the Web That might mean adding a few more drops of filler or using a pinch of hyaluronidase to flatten out any minor puffiness. 
Danielle Sinay, Glamour, 7 Sep. 2022 Fortunately, this can be treated with an injection of hyaluronidase, an enzyme that breaks down the hyaluronic acid in the filler. Sarah Jacoby, SELF, 18 May 2022 Venom from the crotaline family of snakes, such as rattlesnakes, causes damage to capillaries via metalloproteinases and hyaluronidase. Dr. Michael Daignault, USA TODAY, 26 Apr. 2022 In fact, your doctor will be able to dissolve it with an injection of an enzyme called hyaluronidase, which will work its filler-dissolving magic within about 48 hours. Kaitlin Clark, Allure, 9 Feb. 2022 One of the most common gripes doctors have with Sculptra is that there's no equivalent reversal enzyme, like hyaluronidase for HA fillers, in the event that nodules or bumps begin to form. Kaitlin Clark, Allure, 7 Feb. 2022 The side effects are rare and easily managed with antihistamines, corticosteroids, or injections of hyaluronidase. Dori Price, Good Housekeeping, 19 Mar. 2021 Always choose hyaluronic acid fillers Keep in mind that hyaluronic acid is the only type of filler that can be dissolved and reversed using hyaluronidase. Dr. Leslie Baumann, miamiherald, 11 June 2018 Yes, pretty much — hyaluronidase can deflate your fillers like a balloon. Kathleen Hou, The Cut, 9 July 2018 See More
Danielle Sinay, Glamour, 7 Sep. 2022 Fortunately, this can be treated with an injection of hyaluronidase, an enzyme that breaks down the hyaluronic acid in the filler. Sarah Jacoby, SELF, 18 May 2022 Venom from the crotaline family of snakes, such as rattlesnakes, causes damage to capillaries via metalloproteinases and hyaluronidase. Dr. Michael Daignault, USA TODAY, 26 Apr. 2022 In fact, your doctor will be able to dissolve it with an injection of an enzyme called hyaluronidase, which will work its filler-dissolving magic within about 48 hours. Kaitlin Clark, Allure, 9 Feb. 2022 One of the most common gripes doctors have with Sculptra is that there's no equivalent reversal enzyme, like hyaluronidase for HA fillers, in the event that nodules or bumps begin to form. Kaitlin Clark, Allure, 7 Feb. 2022 The side effects are rare and easily managed with antihistamines, corticosteroids, or injections of hyaluronidase. Dori Price, Good Housekeeping, 19 Mar. 2021 Always choose hyaluronic acid fillers Keep in mind that hyaluronic acid is the only type of filler that can be dissolved and reversed using hyaluronidase. Dr. Leslie Baumann, miamiherald, 11 June 2018 Yes, pretty much — hyaluronidase can deflate your fillers like a balloon. Kathleen Hou, The Cut, 9 July 2018 See More Word History
Etymology
International Scientific Vocabulary, from hyaluronic (acid) + -idase (as in glucosidase)
First Known Use
1940, in the meaning defined above
Medical Definition
hyaluronidase
noun
hy·al·uron·i·dase -ˈrän-ə-ˌdās, -ˌdāz
: a mucolytic enzyme that splits and lowers the viscosity of hyaluronic acid facilitating the spreading of fluid through tissues either advantageously (as in the absorption of drugs) or disadvantageously (as in the dissemination of infection), that occurs in many normal tissues, in malignant growths, in invasive bacteria, and in certain venoms, and that is used especially to aid in the dispersion of fluids (as local anesthetics) injected subcutaneously for therapeutic purposes
called also spreading factor