neurofibromatosis
noun
neu·ro·fi·bro·ma·to·sis ˌnu̇r-ō-(ˌ)fī-ˌbrō-mə-ˈtō-səs 
ˌnyu̇r-
: a disorder inherited as an autosomal dominant and characterized especially by brown spots on the skin, neurofibromas of peripheral nerves, and deformities of subcutaneous tissue and bone
Example Sentences
Recent Examples on the Web The exact underlying cause of glioblastoma is unknown in most cases, but in some, it's linked to genetic syndromes: neurofibromatosis type 1, Turcot syndrome and Li Fraumeni syndrome, according to NIH. 
CBS News, 5 Aug. 2022 NF Hope Concert, a benefit for neurofibromatosis, will be held at 7 p.m. Monday, June 27, at the Madden Theatre, 171 E. Chicago Ave. Michelle Mullins, Chicago Tribune, 24 June 2022 Collins was by then a renowned geneticist who had helped to discover key genes behind cystic fibrosis, Type 2 diabetes, Huntington’s disease, neurofibromatosis, and other conditions. Dhruv Khullar, The New Yorker, 7 Apr. 2022 That’s the plan for the annual nationwide Undies Run that benefits research to find cures for neurofibromatosis. oregonlive, 9 Feb. 2022 The combined compounds may suppress the proliferation of neurofibromatosis 2 tumor cells. Annette Bakker, STAT, 15 Dec. 2021 While most see a rhinoceros, Hollant sees his son, who was diagnosed at a young age with neurofibromatosis. Susan Dunne, courant.com, 9 Dec. 2021 Folk’s 21-year-old cousin Blake currently has five brain tumors and has undergone at least 20 surgeries since getting diagnosed with neurofibromatosis as a baby. Globe Staff, BostonGlobe.com, 2 Dec. 2021 Kicker Nick Folk chose the Children’s Tumor Foundation, a nonprofit dedicated to improving the health and well-being of those affected by neurofibromatosis. Globe Staff, BostonGlobe.com, 2 Dec. 2021 See More
CBS News, 5 Aug. 2022 NF Hope Concert, a benefit for neurofibromatosis, will be held at 7 p.m. Monday, June 27, at the Madden Theatre, 171 E. Chicago Ave. Michelle Mullins, Chicago Tribune, 24 June 2022 Collins was by then a renowned geneticist who had helped to discover key genes behind cystic fibrosis, Type 2 diabetes, Huntington’s disease, neurofibromatosis, and other conditions. Dhruv Khullar, The New Yorker, 7 Apr. 2022 That’s the plan for the annual nationwide Undies Run that benefits research to find cures for neurofibromatosis. oregonlive, 9 Feb. 2022 The combined compounds may suppress the proliferation of neurofibromatosis 2 tumor cells. Annette Bakker, STAT, 15 Dec. 2021 While most see a rhinoceros, Hollant sees his son, who was diagnosed at a young age with neurofibromatosis. Susan Dunne, courant.com, 9 Dec. 2021 Folk’s 21-year-old cousin Blake currently has five brain tumors and has undergone at least 20 surgeries since getting diagnosed with neurofibromatosis as a baby. Globe Staff, BostonGlobe.com, 2 Dec. 2021 Kicker Nick Folk chose the Children’s Tumor Foundation, a nonprofit dedicated to improving the health and well-being of those affected by neurofibromatosis. Globe Staff, BostonGlobe.com, 2 Dec. 2021 See More Word History
Etymology
neurofibromat-, Greco-Latin stem of neurofibroma + -osis
First Known Use
1896, in the meaning defined above
Medical Definition
neurofibromatosis
noun
neu·ro·fi·bro·ma·to·sis -fī-ˌbrō-mə-ˈtō-səs
plural neurofibromatoses -ˌsēz
1
also neurofibromatosis type 1 or neurofibromatosis 1 : an inherited developmental disorder characterized especially by brown spots on the skin that are typically present at birth, neurofibromas of peripheral nerves, and deformities of subcutaneous tissues and bone —abbreviation NF, NF-1
called also Recklinghausen's disease, von Recklinghausen's disease
2
also neurofibromatosis type 2 or neurofibromatosis 2 : an inherited disorder characterized by bilateral acoustic neuromas developing in childhood or early adulthood that are typically accompanied by other nonmalignant tumors of the central nervous system —abbreviation NF, NF-2
Note: Both types of neurofibromatosis are inherited as an autosomal dominant trait requiring that one parent pass on a copy of the defective gene on a chromosome other than a sex chromosome. Type 1 is much more common than type 2.