单词	cytokine storm
释义	cytokine storm noun plural cytokine storms : the uncontrolled, sometimes life-threatening, excessive release of cytokines (such as chemokines, interferons, or interleukins) in the body from an aggressive, pro-inflammatory immune response resulting from overreaction of the immune system (as to an infectious disease or immunotherapy) Cytokines are messengers that normally help the body's immune system. But in a cytokine storm far too many are released, and they wind up killing both healthy and diseased cells. Mark Johnson … a cytokine storm is an SOS signal that causes the immune system to launch its entire arsenal of weapons all at once. This last-ditch, kamikaze attack hurts the virus. But it leaves behind tons of collateral damage. Blood vessels take the brunt of it. Michaeleen Doucleff see also cytokine storm syndrome Word History First Known Use 1992, in the meaning defined above Medical Definition cytokine storm noun : the uncontrolled, sometimes life-threatening, excessive release of cytokines (as chemokines, interferons, or interleukins) in the body from an aggressive, pro-inflammatory immune response resulting from overreaction of the immune system (as to an infectious disease or immunotherapy) Glucocorticoids have been used widely for cytokine storm and respiratory failure in patients with Covid-19; however, there is concern that they may prolong viral shedding and lead to secondary infections. David A. Berlin et al., The New England Journal of Medicine The dead had heavier loads of the virus in more tissues and showed clearer signs of a "cytokine storm"—a lethal overreaction of the immune system. Debora MacKenzie, New Scientist see also cytokine storm syndrome
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