: a flask-shaped invagination of a cell's plasma membrane that is involved especially in endocytosis by pinching off and forming vesicles in the cytoplasm
caveolar
ˌka-vē-ˈō-lər
adjective
… clearly of benefit to pathogens, caveolae-dependent endocytosis does not feed into the lysosome pathway and does not result in the degradation of the contents of caveolar vesicles. Jeoung-Sook Shin and Soman N. Abraham
Word History
Etymology
borrowed from New Latin caveola intracellularis, literally, "intracellular pit"; caveola, going back to Medieval Latin, diminutive of Latin cavea "cage, enclosure" — more at cage entry 1
First Known Use
1955, in the meaning defined above
Medical Definition
caveola
noun
cav·e·o·la ˌka-vē-ˈō-lə
plural caveolae -ˌlē
: a flask-shaped invagination of the plasma membrane that is involved especially in endocytosis by pinching off and forming vesicles in the cytoplasm
These findings suggest that the virions entered the cell and were transported to the nucleus through caveolae. Tina Petrogiannis-Haliotis et al., The New England Journal of Medicine
Note: Caveolae are coated by proteins called caveolins and contain larger amounts of cholesterol and glycosphingolipids than the surrounding plasma membrane.