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单词 cathepsin
释义

cathepsin

noun

ca·​thep·​sin kə-ˈthep-sən How to pronounce cathepsin (audio)
: any of several intracellular proteases of animal tissue that aid in autolysis

Example Sentences

Recent Examples on the Web Fortunately, Gerwick had encountered cathepsin inhibitors before. Stephanie Stone, Smithsonian Magazine, 2 Sep. 2021

Word History

Etymology

Greek kathepsein to digest (from kata- cata- + hepsein to boil) + English -in entry 2

First Known Use

1929, in the meaning defined above

Medical Definition

cathepsin

noun

ca·​thep·​sin kə-ˈthep-sən How to pronounce cathepsin (audio)
: any of a class of proteases present in most animal tissues (as in kidney, liver, and spleen) that catalyze the hydrolysis of proteins to polypeptides
Cathepsins are lysosomal proteases that cleave their substrates with relatively low specificity. Arthur M. Krieg et al., Science
Recent investigations by several research groups, working with organisms as diverse as worms and monkeys, implicate cathepsins flooding the cytoplasm as a major cause of necrotic cell death. Nektarios Tavernarakis, New Scientist
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更新时间:2025/2/5 7:47:33