Recent Examples on the WebAllopregnanolone is a neuroactive steroid, structurally similar to progesterone, that acts on GABA receptors and is believed to improve symptoms of depression and anxiety by amplifying GABAergic signaling throughout the brain. Husseini Manji, Scientific American, 14 Sep. 2021 To remedy the situation in the meantime, the group came up with a definition for neonatal abstinence syndrome: any baby who is prenatally exposed to any neuroactive substance and exhibits symptoms is diagnosed with NAS. Naseem S. Miller, OrlandoSentinel.com, 17 Oct. 2017