单词	neuraminidase
释义	neuraminidase noun neur·​amin·​i·​dase ˌnu̇r-ə-ˈmi-nə-ˌdās  ˌnyu̇r-, -ˌdāz : a hydrolytic enzyme that occurs on the surface of the pneumococcus, influenza-causing viruses, and some paramyxoviruses as an antigen and that splits mucoproteins by breaking a glucoside link Example Sentences Recent Examples on the Web Two viruses may have the same broad hemagglutinin and neuraminidase subtypes, but have subtle differences throughout their genome. William A. Haseltine, Forbes, 12 Aug. 2022 The subtyping of the neuraminidase — the N in the virus’ name — is still underway, but the presumption is that the birds and the man were infected with H5N1 viruses. Helen Branswell, STAT, 4 May 2022 The subtypes for influenza A are broken down based on two proteins on the surface of the virus, the CDC explains: hemagglutinin (H) and neuraminidase (N). Korin Miller, Health.com, 18 Nov. 2021 The surface of all influenza strains is studded with proteins, the most important of which, for Influenza A and B, are hemagglutinin (HA) and neuraminidase (NA). New York Times, 8 Dec. 2021 There are 18 different hemagglutinin subtypes and 11 different neuraminidase subtypes (H1 through H18 and N1 through N11). Korin Miller, Health.com, 18 Nov. 2021 As for treatment of avian influenza viruses, the CDC recommends what's known as a neuraminidase inhibitor—like oseltamivir, peramivir, and zanamivir—a type of antiviral drug that can block reproduction of the virus. Maggie O'neill, Health.com, 1 June 2021 Viral code The Hs and Ns refer to hemagglutinin (Ha or H) and neuraminidase (Na or N), respectively, which are both viral molecules that hang on the outside of viral particles. Beth Mole, Ars Technica, 10 Dec. 2019 The flu virus normally infects cells in the lungs by binding through its haemagglutinin and neuraminidase proteins to sialic acid on the surface of lung cells. Neil Savage, Scientific American, 18 Sep. 2019 See More Word History Etymology neuraminic acid, an amino acid + -ide + -ase First Known Use 1957, in the meaning defined above Medical Definition neuraminidase noun neur·​amin·​i·​dase ˌn(y)u̇r-ə-ˈmin-ə-ˌdās, -ˌdāz  : a hydrolytic enzyme that occurs on the surface of the pneumococcus, the orthomyxoviruses, and some paramyxoviruses and that cleaves terminal acetylated neuraminic acids from sugar residues (as in glycoproteins and mucoproteins)
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