单词	gene mutation
释义	gene mutation noun plural gene mutations : a permanent alteration (as by point mutation or frameshift mutation) in the nucleotide sequence of a gene Researchers have identified a gene mutation that's believed to predispose people to malignant melanoma, the deadliest and most aggressive type of skin cancer. Health News compare point mutation Example Sentences Recent Examples on the Web The Food and Drug Administration last May approved Lumakras under its accelerated approval pathway for patients with advanced non-small lung cancer bearing a particular KRAS gene mutation. The Editorial Board, WSJ, 14 Sep. 2022 But, for Wendy Knecht, the bill has been a hard-fought battle that began when she was diagnosed in December 2014 with the BRCA2 gene mutation and a subsequent decision to reduce her risk of breast cancer by having a preventive double mastectomy. Melody Gutierrez, Los Angeles Times, 9 Sep. 2022 For instance, black women are at higher risk for a type of breast cancer known as triple-negative and women of Ashkenazi Jewish heritage are at greater risk of the BRCA gene mutation. The Editorial Board, WSJ, 26 July 2022 Myotonic dystrophy is usually caused by a gene mutation. Julie Washington, cleveland, 16 Apr. 2022 For this test, a blood sample is analyzed to look for a gene mutation that signals the condition. Maggie O'neill, Health.com, 15 Apr. 2022 Even within pairs of twins, one twin who did have the gene mutation could differ in sleep need by an hour or so, and was much more resistant to the effects of sleep deprivation. Erin Berger, Outside Online, 4 Aug. 2014 Women with this gene mutation should undergo more intensive screening for breast, ovarian and colon cancers. Dr. Keith Roach, oregonlive, 20 Jan. 2022 Even though a gene mutation that predisposes someone to cancer hasn't been discovered in my family, my medical teams are certain that genetics play a role. Jessica Baladad As Told To Erica Sweeney, Good Housekeeping, 8 Jan. 2022 See More Word History First Known Use 1904, in the meaning defined above Medical Definition gene mutation noun : a permanent alteration (as a point mutation or frameshift mutation) in the nucleotide sequence of a gene … there is a 50 percent chance each offspring will inherit the gene mutation and may develop the disease. Fred Cicetti In early August the team published a study in Nature that chronicled how a single gene mutation in a laboratory strain of Escherichia coli could create a bacterium resistant to triclosan … Gary Stix
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