: a vesicle formed by the invagination and pinching off of the cell membrane during endocytosis
Example Sentences
Recent Examples on the WebOnce a bad actor is absorbed, these cells have what can best be described as a cellular garbage disposal, called an endosome, that normally shuts the infectious agent down. Brenda Goodman, CNN, 6 Apr. 2022 Then it is engulfed in a hollow bubble called an endosome. Megan Scudellari, Scientific American, 11 Feb. 2022 Although there may be some merit to the argument, recall that SARS-CoV, the virus responsible for the SARS epidemic, also enters cells via the endosome, not by fusion. William A. Haseltine, Forbes, 28 Jan. 2022 On the left hand side lies a separate but interacting pathway that begins in the endosome. William A. Haseltine, Forbes, 22 Sep. 2021 Chloroquine reduces the acidity in endosomes, compartments that cells use to ingest material from the outside and that coronaviruses can use instead of the ACE2 receptor to enter a cell. Kai Kupferschmidt, Science | AAAS, 2 Apr. 2020 Under the stimulus of pain, NK1 receptors actually migrate from the surface of neurons into internal compartments called endosomes, the study found. Bradley J. Fikes, sandiegouniontribune.com, 31 May 2017 See More
Word History
First Known Use
1887, in the meaning defined above
Medical Definition
endosome
noun
en·do·some ˈen-də-ˌsōm
1
: a conspicuous body other than a chromatin granule that occurs within the nuclear membrane of a vesicular protozoan nucleus and is either a karyosome or a nucleolus
2
: a vesicle formed by the invagination and pinching off of the cell membrane during endocytosis