isotretinoin
noun
iso·tret·i·noin ˌī-sō-ˈtre-tə-ˌnȯin 
: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, inhibits sebaceous gland function and keratinization, and is used in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects
Example Sentences
Recent Examples on the Web Overall, though, studies have shown that low-dose isotretinoin is actually pretty well tolerated. 
Gabby Shacknai, Harper's BAZAAR, 25 Aug. 2022 The scientists also identified a potential way to block this scent and stop the spread of the disease, using a medication already known to people struggling with acne, isotretinoin, also known by the trade name Accutane. Sarah Sloat, NBC News, 1 July 2022 Drugmakers have long maintained that there is no direct link between isotretinoin and depression or suicidal ideation. Washington Post, 30 June 2022 For severe acne that’s prone to scarring, oral isotretinoin (a.k.a., Accutane) may be an option. Stacey Colino, Washington Post, 21 June 2022 The cause, in most cases, is unknown, although some cases are caused by genetic changes or the use of isotretinoin, or Accutane medication, during pregnancy. Li Cohen, CBS News, 2 June 2022 These precautions are intense, but dermatologists agree that the final results for isotretinoin are like no other. Sarah Jacoby, SELF, 27 Dec. 2021 Accutane, aka isotretinoin, is a powerful medication used to treat a particular type of severe acne known as recalcitrant nodular acne, according to the US National Library of Medicine's MedlinePlus resource. Korin Miller, Health.com, 20 May 2021 And Accutane — a drug used to treat severe acne — is actually an oral vitamin A called isotretinoin. Julie Ricevuto, Allure, 12 Nov. 2020 See More
Gabby Shacknai, Harper's BAZAAR, 25 Aug. 2022 The scientists also identified a potential way to block this scent and stop the spread of the disease, using a medication already known to people struggling with acne, isotretinoin, also known by the trade name Accutane. Sarah Sloat, NBC News, 1 July 2022 Drugmakers have long maintained that there is no direct link between isotretinoin and depression or suicidal ideation. Washington Post, 30 June 2022 For severe acne that’s prone to scarring, oral isotretinoin (a.k.a., Accutane) may be an option. Stacey Colino, Washington Post, 21 June 2022 The cause, in most cases, is unknown, although some cases are caused by genetic changes or the use of isotretinoin, or Accutane medication, during pregnancy. Li Cohen, CBS News, 2 June 2022 These precautions are intense, but dermatologists agree that the final results for isotretinoin are like no other. Sarah Jacoby, SELF, 27 Dec. 2021 Accutane, aka isotretinoin, is a powerful medication used to treat a particular type of severe acne known as recalcitrant nodular acne, according to the US National Library of Medicine's MedlinePlus resource. Korin Miller, Health.com, 20 May 2021 And Accutane — a drug used to treat severe acne — is actually an oral vitamin A called isotretinoin. Julie Ricevuto, Allure, 12 Nov. 2020 See More Word History
First Known Use
1979, in the meaning defined above
Medical Definition
isotretinoin
noun
iso·tret·i·noin ˌī-sō-ˈtret-ə-ˌnȯin
: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, that inhibits sebaceous gland function and keratinization, and that is administered in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects
called also 13-cis-retinoic acid, retinoic acid
see accutane