mitogenic (ˌmaɪtəʊˈdʒɛnɪk) or mitogenetic (ˌmaɪtədʒɪˈnɛtɪk)
adjective
mitogen in American English
(ˈmaɪtədʒən)
noun
Genetics
any substance that causes a cell to undergo mitosis
Derived forms
mitogenic (ˌmitoˈgenic)
adjective
mitogen in American English
(ˈmaitədʒən, -ˌdʒen)
noun
Biology
any substance or agent that stimulates mitotic cell division
Derived forms
mitogenic (ˌmaitəˈdʒenɪk)
adjective
Word origin
[1950–55; mito(sis) + -gen]This word is first recorded in the period 1950–55. Other words that entered Englishat around the same time include: Common Market, action painting, conflict of interest, drip-dry, hot line-gen is a combining form meaning “that which produces,” used in the formation of compoundwords. Other words that use the affix -gen include: endogen, hydrogen
Examples of 'mitogen' in a sentence
mitogen
This immunologic anergy was similarly observed after mitogen stimulation.
M. Feuerecker, L. Sudhoff, B. Crucian, J.-I. Pagel, C. Sams, C. Strewe, A. Guo, G.Schelling, J. Briegel, I. Kaufmann, A. Choukèr 2018, 'Early immune anergy towards recall antigens and mitogens in patients at onset of septicshock', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-018-19976-w. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hg induced calcium accumulation and activated mitogen-activated protein kinase.
Yun-An Chen, Wen-Chang Chi, Ngoc Nam Trinh, Li-Yao Huang, Ying-Chih Chen, Kai-TengCheng, Tsai-Lien Huang, Chung-Yi Lin, Hao-Jen Huang 2014, 'Transcriptome Profiling and Physiological Studies Reveal a Major Role for AromaticAmino Acids in Mercury Stress Tolerance in Rice Seedlings', PLoS ONE10.1371/journal.pone.0095163. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In addition, anti-proliferative effects on mitogen-activated leukocytes have been demonstrated in vitro.
Stefan Almestrand, Xiao Wang, Åsa Jeppsson-Ahlberg, Marcus Nordgren, Jenny Flygare,Birger Christensson, Stephan Rössner, Birgitta Sander 2015, 'Influence of rimonabant treatment on peripheral blood mononuclear cells; flow cytometryanalysis and gene expression profiling', PeerJhttps://peerj.com/articles/1056.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
There was no difference when the lymphocytes were stimulated by the mitogen.
Pavlica Ljiljana, Pejnović Nada, Drašković Nada 2003, 'Cell-mediated immune response of synovial fluid lymphocytes to ureaplasma antigenin Reiter's syndrome', Srpski Arhiv za Celokupno Lekarstvohttp://www.doiserbia.nb.rs/img/doi/0370-8179/2003/0370-81790308285P.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We reviewed articles examining mitogen-activated protein kinases using prostate tissue or cell lines.
Koul Sweaty, Maroni Paul D, Meacham Randall B, Koul Hari K 2004, 'Mitogen Activated Protein kinase signal transduction pathways in the prostate', Cell Communication and Signalinghttp://www.biosignaling.com/content/2/1/5. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This receptor upregulation occurs via activation of the mitogen-activated protein kinase pathway.
Nilsson Ola, Säveland Hans, Ahnstedt Hilda, Edvinsson Lars 2011, 'Human cerebrovascular contractile receptors are upregulated via a B-Raf/MEK/ERK-sensitivesignaling pathway', BMC Neurosciencehttp://www.biomedcentral.com/1471-2202/12/5. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Treatment with #1 resulted in mitochondrial depolarization followed by mitogen-activated protein kinase activation.
Fumi Sato-Kaneko, Xiaodong Wang, Shiyin Yao, Tadashi Hosoya, Fitzgerald S. Lao, KarenMesser, Minya Pu, Nikunj M. Shukla, Howard B. Cottam, Michael Chan, Dennis A. Carson,Maripat Corr, Tomoko Hayashi 2018, 'Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy',BioMed Research Internationalhttp://dx.doi.org/10.1155/2018/8091283. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)