Metabolic engineering could be an efficient technology for production of ginsenoside sapogenin.
Yu Shin Gwak, Jung Yeon Han, Yong Eui Choi 2019, 'Production of ginsenoside aglycone (protopanaxatriol) and male sterility of transgenictobacco co-overexpressing three Panax ginseng genes: PgDDS, CYP716A47, and CYP716A53v2',Journal of Ginseng Researchhttp://www.sciencedirect.com/science/article/pii/S1226845317303184. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Iron–sapogenin nanoparticle shows significantly better effects than the sapogenin.
Qian Yang, Chuang Zhao, Jun Zhao, Yong Ye 2017, 'Synthesis and neuroprotective effects of the complex nanoparticles of iron and sapogeninisolated from the defatted seeds of Camellia oleifera', Pharmaceutical Biologyhttp://dx.doi.org/10.1080/13880209.2016.1245346. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, sapogenin has been isolated and shows antioxidative, anti-inflammatory and analgesic activities suggestive of its neuroprotective function.
Qian Yang, Chuang Zhao, Jun Zhao, Yong Ye 2017, 'Synthesis and neuroprotective effects of the complex nanoparticles of iron and sapogeninisolated from the defatted seeds of Camellia oleifera', Pharmaceutical Biologyhttp://dx.doi.org/10.1080/13880209.2016.1245346. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)