a disease characterized by deep bronzing of the skin, anaemia, and extreme weakness, caused by underactivity of the adrenal glands
Also called: adrenal insufficiency
Word origin
C19: named after Thomas Addison (1793–1860), British physician who identified it
Examples of 'adrenal insufficiency' in a sentence
adrenal insufficiency
Central hypothyroidism and adrenal insufficiency may occur.
Medeiros CB, Bordallo AP, Souza FM, Collett-Solberg PF 2013, 'Endocrine management of children with Prader–Willi syndrome', Pediatric Health, Medicine and Therapeuticshttp://www.dovepress.com/endocrine-management-of-children-with-praderndashwilli-syndrome-a14761. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Blood tests were compatible with adrenal insufficiency.
Clara Preto, José Eduardo Alves, Marcelo Fonseca, Manuela Santos, Natalina Miguel 2018, 'Dark skin - constitutional or pathological? A X-linked Adrenoleukodystrophy case report',Nascer e Crescerhttps://revistas.rcaap.pt/nascercrescer/article/view/12753. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Adrenal function tests revealed adrenal insufficiency.
Bures Vladimir, Borusiak Peter, Heldmann Michael, Gerner Patrick, Wirth Stefan 2005, 'Adrenal failure followed by status epilepticus and hemolytic anemia in primary antiphospholipidsyndrome', Thrombosis Journalhttp://www.thrombosisjournal.com/content/3/1/6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Moreover, fdx1b−/− mutants exhibit crucial features of primary adrenal insufficiency, and mirror metabolic changes detected in primary adrenal insufficiency patients.
Meltem Weger, Benjamin D. Weger, Benjamin Görling, Gernot Poschet, Melek Yildiz, RüdigerHell, Burkhard Luy, Teoman Akcay, Tülay Güran, Thomas Dickmeis, Ferenc Müller, NilsKrone 2018, 'Glucocorticoid deficiency causes transcriptional and post-transcriptional reprogrammingof glutamine metabolismResearch in context section', EBioMedicinehttp://www.sciencedirect.com/science/article/pii/S2352396418303827. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The acute adrenal insufficiency recovered after appropriate antibiotic therapy.
Suman S Karanth, Anurag Gupta, Mukhyaprana Prabhu 2012, 'Community acquired bilateral upper lobe Pneumonia with acute adrenal insufficiency:A new face of Achromobacter xylosoxidans', Australasian Medical Journalhttp://amj.net.au/index.php?journal=AMJ&page=article&op=view&path%5B%5D=1279&path%5B%5D=992. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Endocrine work-up ruled out hypothyroidism and adrenal insufficiency.
Weeraporn Srisung, Aumyot Prongdong, Pavis Laengvejkal, Sorot Phisitkul 2015, 'Acute motor and sensory axonal neuropathy-associated syndrome of inappropriate antidiuretichormone secretion', Southwest Respiratory and Critical Care Chronicleshttp://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/226. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The mechanisms of septic shock-associated adrenal insufficiency remain unclear.
Andrea Polito, Romain Sonneville, Céline Guidoux, Lucinda Barrett, Odile Viltart,Virginie Mattot, Shidasp Siami, Geoffroy Lorin de la Grandmaison, Fabrice Chrétien,Mervyn Singer, Françoise Gray, Djillali Annane, Jean-Philippe Brouland, Tarek Sharshar 2011, 'Changes in CRH and ACTH synthesis during experimental and human septic shock.', PLoS ONEhttp://europepmc.org/articles/PMC3207830?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A physical examination and laboratory evaluation suggested primary adrenal insufficiency.
Mohammad Alkhateeb, Mohammad Alsakkal, Mohammad Nour Alfauri, Diana Alasmar 2018, 'Reversible dilated cardiomyopathy as a complication of adrenal cortex insufficiency:a case report', Journal of Medical Case Reportshttp://link.springer.com/article/10.1186/s13256-018-1899-1. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Laboratory results revealed hypothyroidism, hypoglycemia, hypoprolactinemia, and adrenalinsufficiency.
Shinya Matsuzaki, Masayuki Endo, Yutaka Ueda, Kazuya Mimura, Aiko Kakigano, TomomiEgawa-Takata, Keiichi Kumasawa, Kiyoshi Yoshino, Tadashi Kimura 2017, 'A case of acute Sheehan's syndrome and literature review: a rare but life-threateningcomplication of postpartum hemorrhage', BMC Pregnancy and Childbirthhttp://link.springer.com/article/10.1186/s12884-017-1380-y. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
It frequently presents bilaterally and with symptoms of adrenal insufficiency.
Catarina Roque, Ricardo Fonseca, Carlos Tavares Bello, Carlos Vasconcelos, AntónioGalzerano, Sância Ramos 2017, 'Thyrotoxicosis leading to adrenal crises reveals primary bilateral adrenal lymphoma',Endocrinology, Diabetes & Metabolism Case Reportshttps://www.edmcasereports.com/articles/endocrinology-diabetes-and-metabolism-case-reports/10.1530/EDM-17-0002. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)