an organic chemical that bonds with metal ions and produces a chelate compound
Examples of 'chelator' in a sentence
chelator
After rewarming, injury increased especially after cold incubation in chelator-free solutions.
Anja Bienholz, Björn Walter, Gesine Pless-Petig, Hana Guberina, Andreas Kribben, OliverWitzke, Ursula Rauen 2017, 'Characterization of injury in isolated rat proximal tubules during cold incubationand rewarming', PLOS ONE10.1371/journal.pone.0180553. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The sequestration of iron with an iron chelator prevented the iron-mediated biofilm stimulation.
Euna Oh, Katelyn J. Andrews, Byeonghwa Jeon 2018, 'Enhanced Biofilm Formation by Ferrous and Ferric Iron Through Oxidative Stress inCampylobacter jejuni', Frontiers in Microbiologyhttps://www.frontiersin.org/article/10.3389/fmicb.2018.01204/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Treating cells with iron chelator tropolone yielded similar results.
Ye Liu, Lanhua Yi, Lanhua Yi, Changqing Ruan, Changqing Ruan, Shixiang Yao, ShixiangYao, Lili Deng, Lili Deng, Kaifang Zeng, Kaifang Zeng 2019, 'Proline Increases Pigment Production to Improve Oxidative Stress Tolerance and BiocontrolAbility of Metschnikowia citriensis', Frontiers in Microbiologyhttps://www.frontiersin.org/article/10.3389/fmicb.2019.01273/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Desferal as an iron chelator can be ended renal complication.
Mandana Zafari, Azar Aghamohammady 2017, 'Comparison of Beta-2 Microglobulin Level and Some Variables Between Thalassemia MajorPatients Who Treated by Desferal and Control Group', Zahedan Journal of Researches in Medical Scienceshttp://dx.doi.org/10.5812/zjrms.11538. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Chelator treatment resulted in the generation of processes containing the presynaptic marker synaptophysin.
Pabla Aguirre, Natalia P Mena, Carlos M Carrasco, Yorka Muñoz, Patricio Pérez-Henríquez,Rodrigo A Morales, Bruce K Cassels, Carolina Méndez-Gálvez, Olimpo García-Beltrán,Christian González-Billault, Marco T Núñez 2015, 'Iron Chelators and Antioxidants Regenerate Neuritic Tree and Nigrostriatal Fibersof MPP+/MPTP-Lesioned Dopaminergic Neurons.', PLoS ONEhttp://europepmc.org/articles/PMC4684383?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These effects were canceled by the addition of the iron chelator, deferoxamine.
Tsutomu Miyamoto, Hiroyasu Kashima, Yasushi Yamada, Hisanori Kobara, Ryoichi Asaka,Hirofumi Ando, Shotaro Higuchi, Koichi Ida, David Hamisi Mvunta, Tanri Shiozawa 2016, 'Lipocalin 2 Enhances Migration and Resistance against Cisplatin in Endometrial CarcinomaCells.', PLoS ONEhttp://europepmc.org/articles/PMC4864227?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cadherin-11 was bound via histidine tag to lipid membranes with chelator head groups.
Alexander Körner, Christina Deichmann, Fernanda F. Rossetti, Almut Köhler, Oleg V.Konovalov, Doris Wedlich, Motomu Tanaka 2013, 'Cell Differentiation of Pluripotent Tissue Sheets Immobilized on Supported MembranesDisplaying Cadherin-11', PLoS ONE10.1371/journal.pone.0054749. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Chromatographic analyses showed that this species produced oxalic acid as sole metal chelator.
Edith eJoseph, Edith eJoseph, Sylvie eCario, Anaële eSimon, Marie eWörle, Rocco eMazzeo,Pilar eJunier, Daniel eJob 2012, 'Protection of metal artefacts with the formation of metal-oxalates complexes by Beauveriabassiana.', Frontiers in Microbiologyhttp://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00270/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The patient was administered a chelator treatment with rapid improvement of the symptoms.
Halima Muller, Simon Regard, Nicole Petriccioli, Omar Kherad 2013, 'Traditional medicine: a rare cause of lead poisoning in Western countries [v1; refstatus: indexed, http://f1000r.es/2c6]', F1000Researchhttp://f1000research.com/articles/2-250/v1. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The iron chelator desferoxamine reduced both iron uptake and colony formation.
Messner Donald J, Kowdley Kris V 2008, 'Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-boundiron', BMC Gastroenterologyhttp://www.biomedcentral.com/1471-230X/8/2. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)