an anticonvulsant drug used in the management of epilepsy
carbamazepine in American English
(ˌkɑːrbəˈmæzəˌpin)
noun
Pharmacology
a white to whitish toxic powder, C15H12N2O, used as an analgesic in the treatment of trigeminal neuralgia and as an anticonvulsant
Word origin
[carbam(oyl) + azepine, components of the chemical name]
Examples of 'carbamazepine' in a sentence
carbamazepine
Her seizures were controlled with carbamazepine treatment.
Melek Kandemir, Zerrin Pelin, Cem İsmail Küçükali, Nuriye Yılmaz 2010, 'A Case with Bilateral Periventricular Nodular Heterotopia Diagnosed as Depression',Türk Nöroloji Dergisihttp://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-04274&look4=. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Our patient gave no response to indomethacin, gabapentine and carbamazepine treatments.
Hakan Levent Gül, Ömer Karadaş 2014, 'A Case of Resistant SUNCT that Gave Response to Steroid Treatment', Türk Nöroloji Dergisihttp://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-60320. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Medication adherence, adverse effects, seizure control and carbamazepine blood levels were monitored.
Priyadarshani Galappatthy, Chiranthi Kongala Liyanage, Marianne Nishani Lucas, DiliniT. L. M. Jayasekara, Sachith Aloka Abhayaratna, Chamari Weeraratne, Kusum De Abrew,Padma Sriyani Gunaratne, Ranjani Gamage, Chandrika N. Wijeyaratne 2018, 'Obstetric outcomes and effects on babies born to women treated for epilepsy duringpregnancy in a resource limited setting: a comparative cohort study', BMC Pregnancy and Childbirthhttp://link.springer.com/article/10.1186/s12884-018-1857-3. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These results suggest that carbamazepine acts as a β-adrenergic antagonist.
Harold Ray Garner, Mark Burkart, Cristi Lara Galindo, Amina Torkia Tassa, Mounir Errami 2010, 'Carbamazepine alone and in combination with doxycycline attenuates isoproterenol-inducedcardiac hypertrophy', Heart Internationalhttp://www.pagepress.org/journals/index.php/hi/article/view/200. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Oral carbamazepine treatment was stopped, but blood tests showed acute liver and acute renal failure.
Yuko Ono, Tsuyoshi Shimo, Yoshinori Shirafuji, Toshihisa Hamada, Masanori Masui, KyoichiObata, Mayumi Yao, Koji Kishimoto, Akira Sasaki 2016, 'Drug-Induced Hypersensitivity Syndrome Caused by Carbamazepine Used for the Treatmentof Trigeminal Neuralgia', Case Reports in Dentistryhttp://dx.doi.org/10.1155/2016/4605231. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Carbamazepine was used as internal standard in all analyses.
Sakine ATILA KARACA, Işıl Tan YILMAZ, Erol ŞENER, Duygu YENİCELİ UĞUR 2016, 'Development and Validation of a New HPLC Method for the Determination of Quetiapineand Its Metabolites 7- Hydroxy Quetiapine and Quetiapine Sulfoxide in Rat Plasma',Turkish Journal of Pharmaceutical Scienceshttp://www.turkjps.org/archives/archive-detail/article-preview/development-and-validation-of-a-new-hplc-method-fo/12284. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Among the anti-epileptic agents examined, valproate, carbamazepine and ethosuximide, significantly inhibited nicotine-induced tremor.
Naofumi Kunisawa, Saki Shimizu, Masaki Kato, Higor A. Iha, Chihiro Iwai, Mai Hashimura,Mizuki Ogawa, Shohei Kawaji, Kazuma Kawakita, Keisuke Abe, Yukihiro Ohno 2018, 'Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremorand anti-epileptic agents', Journal of Pharmacological Scienceshttp://www.sciencedirect.com/science/article/pii/S1347861318300884. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Active ingredients - thiotriazolin with carbamazepine (1.5: 1), excipients (fillers, disintegrants, binders, grease).
L. I. Kucherenko, G. R. Nimenko, Z. B. Moryak 2017, 'EXCIPIENTS CHOICE TO OBTAIN TABLETS BASED ON CARBAMAZEPINE AND THIOTRIAZOLIN BY METHODOF WET GRANULATION', Фармацевтичний часописhttps://ojs.tdmu.edu.ua/index.php/pharm-chas/article/view/7884. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The study involved 40 paediatric epileptic patients on steady-state carbamazepine treatment.
Milovanovic Dragana Dragas, Radosavljevic Ivan, Radovanovic Marija, Milovanovic JasminaR., Obradovic Slobodan, Jankovic Slobodan, Milovanovic Dragan, Djordjevic Natasa 2015, 'CYP3A5 Polymorphism In Serbian Paediatric Epileptic Patients On Carbamazepine Treatment',Serbian Journal of Experimental and Clinical Researchhttp://www.degruyter.com/view/j/sjecr.2015.16.issue-2/sjecr-2015-0012/sjecr-2015-0012.xml?format=INT. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Carbamazepine and 10,11-epoxide-carbamazepine concentrations were analyzed through high-performance liquid chromatography.
Chahra Chbili, Anis Hassine, Aicha Laouani, Sana Ben Amor, Manel Nouira, Sofiène BenAmmou, Saad Saguem 2016, 'The relationship between pharmacokinetic parameters of carbamazepine and therapeuticresponse in epileptic patients', Archives of Medical Sciencehttps://www.termedia.pl/The-relationship-between-pharmacokinetic-parameters-of-carbamazepine-and-therapeutic-response-in-epileptic-patients,19,27635,1,1.html. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)