a former region of E France: mainly mountainous, rising to the edge of the Massif Central in the west and the French Alps in the east; drained by the Rivers Rhône, Saône, and Isère
Rhône-Alpes in American English
(roʊnˈælp; roʊnˈɑlp; French ʀoʊnˈalp)
metropolitan region of SE France: 16,872 sq mi (43,698 sq km); pop. 5,351,000; chief city, Lyon