Epilepsy should be treated from the onset with anticonvulsive therapy.
Berardo Rinaldi, Alessandro Vaisfeld, Sergio Amarri, Chiara Baldo, Giuseppe Gobbi,Pamela Magini, Erto Melli, Giovanni Neri, Francesca Novara, Tommaso Pippucci, RomanaRizzi, Annarosa Soresina, Laura Zampini, Orsetta Zuffardi, Marco Crimi 2017, 'Guideline recommendations for diagnosis and clinical management of Ring14 syndrome—firstreport of an ad hoc task force', Orphanet Journal of Rare Diseaseshttp://link.springer.com/article/10.1186/s13023-017-0606-4. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These substances have therefore been suggested to contribute to the anticonvulsive effect of the diet.
Jenny Tigerholm, Sara I Börjesson, Linnea Lundberg, Fredrik Elinder, Erik Fransén 2012, 'Dampening of hyperexcitability in CA1 pyramidal neurons by polyunsaturated fatty acidsacting on voltage-gated ion channels.', PLoS ONEhttp://europepmc.org/articles/PMC3458057?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Besides seizures, the nerves can also be damaged by anticonvulsive therapy.
Khalil Ahmad, Saeed Bin Ayaz, Heyyan Bin Khalil, Sumeera Matee 2017, 'Bilateral spontaneous anterior shoulder dislocation: A missed orthopedic injury mistakenas proximal neuropathy', Chinese Journal of Traumatologyhttp://www.sciencedirect.com/science/article/pii/S1008127517300202. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Despite aggressive anticonvulsive therapy, his seizures only abated with initiation of ganciclovir therapy.
Fernanda Leite de Souza Franceschi, Jaime Green, Zuzan Cayci, Evan Mariash, MustaphaEzzeddine, Veronika Bachanova, Celalettin Ustun 2014, 'Human Herpesvirus 6 is Associated with Status Epilepticus and Hyponatremia after UmbilicalCord Blood Transplantation', Canadian Journal of Infectious Diseases and Medical Microbiologyhttp://dx.doi.org/10.1155/2014/392720. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The use of anticonvulsive agents can be problematic as well.
Stephane Legriel, Gretchen M. Brophy 2016, 'Managing Status Epilepticus in the Older Adult', Journal of Clinical Medicinehttp://www.mdpi.com/2077-0383/5/5/53. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In the case of the latter, catatonia mostly resolves when the seizures respond to the anticonvulsive treatment.
Ragnar Verbraeken, Jurjen J. Luykx 2018, 'Persistent catatonia following epileptic seizures: a case report and systematic literaturesearch', BMC Psychiatryhttp://link.springer.com/article/10.1186/s12888-018-1935-0. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cases were defined as patients who developed seizures that required initiation of anticonvulsive therapy within48 h of surgery.
Felix R Montes, Daniel F Pardo, Marisol Carreño, Catalina Arciniegas, Rodolfo J Dennis,Juan P Umaña 2012, 'Risk factors associated with postoperative seizures in patients undergoing cardiacsurgery who received tranexamic acid: A case-control study', Annals of Cardiac Anaesthesiahttp://www.annals.in/article.asp?issn=0971-9784;year=2012;volume=15;issue=1;spage=6;epage=12;aulast=Montes. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Several animal and human investigations suggest anxiolytic, mood stabilizer, sedative, analgesic, and anticonvulsive and neuroprotective properties for lavender.
Peir Hossein Koulivand, Maryam Khaleghi Ghadiri, Ali Gorji 2013, 'Lavender and the Nervous System', Evidence-Based Complementary and Alternative Medicinehttp://dx.doi.org/10.1155/2013/681304. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)