Staining confirmed the presence of carbonic anhydrase, particularly on the ridges of septae.
Ian M Sandeman 2012, 'Preliminary results with a torsion microbalance indicate that carbon dioxide and exposedcarbonic anhydrase in the organic matrix are the basis of calcification on the skeletonsurface of living corals', Revista de Biología Tropicalhttp://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S0034-77442012000500010. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hypotheses include carbonic anhydrase activity, calcium and metal cation sequestration, and xenobiotic transport.
Matan Shelomi 2017, 'De novo transcriptome analysis of the excretory tubules of Carausius morosus (Phasmatodea)and possible functions of the midgut 'appendices'.', PLoS ONEhttp://europepmc.org/articles/PMC5383107?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Also, carbonic anhydrase activity was observed in three of these isolated bacteria.
G. A. Silva-Castro, I. Uad, A. Gonzalez-Martinez, A. Rivadeneyra, J. Gonzalez-Lopez,M. A. Rivadeneyra 2015, 'Bioprecipitation of Calcium Carbonate Crystals by Bacteria Isolated from Saline EnvironmentsGrown in Culture Media Amended with Seawater and Real Brine', BioMed Research Internationalhttp://dx.doi.org/10.1155/2015/816102. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Calcification ceased in the presence of the carbonic anhydrase inhibitor azolamide.
Ian M Sandeman 2012, 'Preliminary results with a torsion microbalance indicate that carbon dioxide and exposedcarbonic anhydrase in the organic matrix are the basis of calcification on the skeletonsurface of living corals', Revista de Biología Tropicalhttp://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S0034-77442012000500010&lng=en&tlng=en. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In mechanically ventilated patients, carbonic anhydrase inhibitor therapy may decrease the duration of mechanical ventilation.
Bassem Y Tanios, Maryam O Omran, Carlos Noujeim, Tamara Lotfi, Samir S Mallat, PierreK Bou-Khalil, Elie A Akl, Houssam S Itani 2018, 'Carbonic anhydrase inhibitors in patients with respiratory failure and metabolic alkalosis:a systematic review and meta-analysis of randomized controlled trials', Critical Carehttp://link.springer.com/article/10.1186/s13054-018-2207-6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Methanogenic carbonic anhydrase and acetate kinase were directly activated by cadmium.
Elizabeth Lira-Silva, M Geovanni Santiago-Martínez, Viridiana Hernández-Juárez, RodolfoGarcía-Contreras, Rafael Moreno-Sánchez, Ricardo Jasso-Chávez 2012, 'Activation of methanogenesis by cadmium in the marine archaeon Methanosarcina acetivorans.',PLoS ONEhttp://europepmc.org/articles/PMC3495967?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Sulphonamides have been known for decades as carbonic anhydrase inhibitors and are in clinical use.
Taner Gokcen, Melike Al, Meryem Topal, Ilhami Gulcin, Turan Ozturk, Ahmet C. Goren 2017, 'Synthesis of some natural sulphonamide derivatives as carbonic anhydrase inhibitors',Organic Communicationshttp://www.acgpubs.org/OC/2017/Volume%2010/Issue%201/4-OC-1605-418.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Carbonic anhydrase inhibitors may be effective to treat this condition.
Pautler SE, Browning DJ 2014, 'Isolated posterior uveal effusion: expanding the spectrum of the uveal effusion syndrome',Clinical Ophthalmologyhttp://www.dovepress.com/isolated-posterior-uveal-effusion-expanding-the-spectrum-of-the-uveal--peer-reviewed-article-OPTH. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Acetazoleamide, a potent carbonic anhydrase inhibitor, has significantly prevented the occurrence of these ulcers.
B. Djahanguiri 1970, 'The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in GuineaPig', Acta Medica Iranicahttp://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/7000.pdf&manuscript_id=7000. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Acetazolamide, a carbonic anhydrase inhibitor and atypical antiseizure medication, decreases seizures in four patients.
Jenna Klotz, Brenda E Porter, Claire Colas, Avner Schlessinger, Ana M Pajor 2016, 'Mutations in the Na+/Citrate Cotransporter NaCT (SLC13A5) in Pediatric Patients withEpilepsy and Developmental Delay', Molecular Medicinehttp://link.springer.com/article/10.2119/molmed.2016.00077. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)