Inability of sweating can even result in serious health effects in humans affected by anhidrosis.
Patricia Klaka, Sabine Grüdl, Bernhard Banowski, Melanie Giesen, Andrea Sättler, PeterProksch, Thomas Welss, Thomas Förster 2017, 'A novel organotypic 3D sweat gland model with physiological functionality', PLOS ONE10.1371/journal.pone.0182752. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Classically, the clinical triad consists of ipsilateral blepharoptosis, pupillary miosis, and facial anhidrosis.
Padungkiatsagul T, Poonyathalang A, Jindahra P, Cheecharoen P, Vanikieti K 2018, 'Isolated Horner syndrome as a rare initial presentation of nasopharyngeal carcinoma:a case report', International Medical Case Reports Journalhttps://www.dovepress.com/isolated-horner-syndrome-as-a-rare-initial-presentation-of-nasopharyng-peer-reviewed-article-IMCRJ. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A 30-year -old man was seen for acquired anhidrosis.
Nair Laxmi, Beena D, Manohar S 1992, 'Acquired anhidrosis a case report', Indian Journal of Dermatology, Venereology and Leprologyhttp://www.ijdvl.com/article.asp?issn=0378-6323;year=1992;volume=58;issue=2;spage=111;epage=112;aulast=Nair. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A case of progressive isolated segmental anhidrosis has also been described.
Sawhney M, Sharma Y, Singh N 2004, 'Segmental anhidrosis with hyporeflexia associated with congenital spinal deformity:A Ross's syndrome variant or inverse Horner's syndrome?', Indian Journal of Dermatology, Venereology and Leprologyhttp://www.ijdvl.com/article.asp?issn=0378-6323;year=2004;volume=70;issue=1;spage=29;epage=32;aulast=Sawhney. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Ectodermal dysplasias are rare conditions with a triad of hypotrichosis, anodontia and anhidrosis.
Elif Oral Ahiskalioglu, Ali Ahiskalioglu, Binali Firinci, Aysenur Dostbil, MehmetAksoy 2015, 'Anesthetic management of a pediatric patient with hypohidrotic ectodermal dysplasiaundergoing emergency surgery', Brazilian Journal of Anesthesiologyhttp://www.sciencedirect.com/science/article/pii/S0104001413002327. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Among the 18 patients, 11 had hypohidrosis or anhidrosis.
Sahuc P, Chiche L, Dussol B, Pouget J, Franques J 2016, 'Sudoscan as a noninvasive tool to assess sudomotor dysfunction in patients with Fabrydisease: results from a case–control study', Therapeutics and Clinical Risk Managementhttps://www.dovepress.com/sudoscan-as-a-noninvasive-tool-to-assess-sudomotor-dysfunction-in-pati-peer-reviewed-article-TCRM. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The clinical triad consists of hypodontia, hypotrichosis, and anhidrosis with otheradditional symptoms.
Kuei-Chung Liu, Ching-Yuang Huang, Sheau-Chiou Chao 2012, 'Anhidrotic ectodermal dysplasia—A case series in a medical center in southern Taiwan',Dermatologica Sinicahttp://www.sciencedirect.com/science/article/pii/S1027811712000353. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Patients with congenital insensitivity to pain with anhidrosis lack pain sensation, but they may have tactile hyperesthesia.
Cong Wang, Xianwei Zhang, Shanna Guo, Jiaoli Sun, Ningbo Li 2017, 'Anesthetic management during adenotonsillectomy for twins with congenital insensitivityto pain with anhidrosis: two case reports', Journal of Medical Case Reportshttp://link.springer.com/article/10.1186/s13256-017-1406-0. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We reported a 22-year-old male with generalized anhidrosis, except axillae, forehead, palms and soles, since infancy.
Chih-Ting Chen, Ding-Dar Lee 2018, 'Idiopathic generalized anhidrosis with absence of sweat glands: A case report andliterature review', Dermatologica Sinicahttp://www.sciencedirect.com/science/article/pii/S1027811717302136. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Based on clinical as well as compatible histological features a diagnosis of congenital insensitivity to pain with anhidrosis was made.
Carounanidy Udayashankar, P Oudeacoumar, Amiya Kumar Nath 2012, 'Congenital insensitivity to pain and anhidrosis: A case report from South India',Indian Journal of Dermatologyhttp://www.e-ijd.org/article.asp?issn=0019-5154;year=2012;volume=57;issue=6;spage=503;epage=503;aulast=Udayashankar. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)