(ˌaɪsəʊˈprɛnəˌliːn) or US isoproterenol (ˌaɪsəʊprəˈtɜːrəˌnɒl)
noun
drugs
a compound that is a derivative of adrenaline and that is used to treat asthma and bronchial conditions. Formula: C11H17NO3
isoproterenol in American English
(ˌaisəprouˈterəˌnɔl, -ˌnɑl)
noun
Pharmacology
a beta-adrenergic receptor agonist, C11H17NO3, used as a bronchodilator
Word origin
[1955–60; isopro(pyl) + (Ar)terenol trade name for a hydrochloride of norepinephrine]This word is first recorded in the period 1955–60. Other words that entered Englishat around the same time include: backgrounder, life-support, opioid, rite of passage, rollout
Examples of 'isoproterenol' in a sentence
isoproterenol
We tested the effects of klotho on cell apoptosis in isoproterenol-treated cardiomyocytes.
Shuang Song, Pan Gao, Hang Xiao, Yan Xu, Lian Yi Si 2013, 'Klotho Suppresses Cardiomyocyte Apoptosis in Mice with Stress-Induced Cardiac Injuryvia Downregulation of Endoplasmic Reticulum Stress', PLoS ONE10.1371/journal.pone.0082968. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The effect of isoproterenol was reversed by the antagonist propranolol.
Sher Zaman Safi, Humaira Shah, Rajes Qvist, Priyadarshni Bindal, Marzida Mansor,Gracie Ong Siok Yan, Ikram Shah Bin Ismail 2018, 'Beta Adrenergic Receptors Stimulation Attenuates Phosphorylation of NF-κB and IκBαin Hyperglycemic Endothelial Cells', Cellular Physiology and Biochemistryhttps://www.karger.com/Article/FullText/495591. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Intravenous isoproterenol infusion successfully suppressed the malignant arrhythmia.
Patrick Badertscher, Michael Kuehne, Beat Schaer, Christian Sticherling, Stefan Osswald,Tobias Reichlin 2017, 'Case report: electrical storm during induced hypothermia in a patient with early repolarization',BMC Cardiovascular Disordershttp://link.springer.com/article/10.1186/s12872-017-0711-2. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cardioprotective potential was evaluated against isoproterenol induced cardiotoxicity.
Nazish Jahan*, Khalil-ur-Rahman, Shaukat Ali, M. Rafiq Asi1 and Ajaz Akhtar2 2012, 'Cardioprotective Potential of Gemmomodified Extract of Terminalia arjuna against ChemicallyInduced Myocardial Injury in Rabbits', Pakistan Veterinary Journalhttp://pvj.com.pk/pdf-files/32_2/255-259.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Contractility was evaluated in isolated hearts, challenged with isoproterenol.
Álvaro Valdés, Adriana V. Treuer, Guillermo Barrios, Nikol Ponce, Roberto Fuentealba,Raul A. Dulce, Daniel R. González 2018, 'NOX Inhibition Improves β-Adrenergic Stimulated Contractility and Intracellular CalciumHandling in the Aged Rat Heart', International Journal of Molecular Scienceshttp://www.mdpi.com/1422-0067/19/8/2404. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Administration of quercetin significantly ameliorated myocardial oxidative injury and immunity function impairment induced by isoproterenol.
Shaoping Lu, Lei Zhang, Hui Liu 2012, 'Evaluation of Antioxidant and Immunity Activities of Quercetin in Isoproterenol-TreatedRats', Moleculeshttp://www.mdpi.com/1420-3049/17/4/4281/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This effect was no longer observed when the individual received isoproterenol infusionswhile not meditating.
Sahib S Khalsa, Sahib S Khalsa, Sahib S Khalsa, David eRudrauf, Richard J Davidson,Daniel eTranel 2015, 'The effect of meditation on regulation of internal body states', Frontiers in Psychologyhttp://journal.frontiersin.org/Journal/10.3389/fpsyg.2015.00924/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The levels altered by isoproterenol were restored significantly by the administration of the extract.
Pavan Kumar, G. Balamurugan, P. Muralidharan 2008, 'Inotropic and cardioprotective effects of Daucus carota Linn. on isoproterenol-inducedmyocardial infarction', Bangladesh Journal of Pharmacologyhttp://www.bdjpharmacol.com/0302/74.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Isoproterenol increased both atrial frequency and contractility but glucagon onlyenhanced atrial rate.
Beatriz Merino, Ivan Quesada, Jesús Hernández-Cascales 2015, 'Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparisonwith Isoproterenol', PLOS ONE10.1371/journal.pone.0132884. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)