If you say that something happens or should happen irrespective of a particular thing, you mean that it is not affected or should not be affected by that thing.
[formal]
We believe in investing in our people, irrespective of age. [+ of]
This service should be available to everybody, irrespective of whether they can affordit.
See full dictionary entry for irrespective
irrespective of in British English
(preposition)
without taking account of; regardless of
See full dictionary entry for irrespective
irrespective of in American English
regardless of; independent of
See full dictionary entry for irrespective
Examples of 'irrespective of' in a sentence
irrespective of
I've never been able to do that and I invariably end up speaking my mind, irrespective of who gets hurt in the process.
MacNeill, Alastair CODE BREAKER
It was always the same, he just couldn't turn down a challenge, irrespective of the harm it could do to himself or to UNACO in general.